PPOX Products

Description

PPOX encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified.

Bioinformatics

Entrez	5498 Human
Uniprot	AAH02357 Human NM_000309 Human NP_000300 Human NP_000300.1 Human NP_001116236 Human P50336 Human
Product By Gene ID	5498
Alternate Names	EC 1.3.3.4 MGC8485 PPOVP protoporphyrinogen oxidase V290M variegate porphyria

Research Areas for PPOX

Find related products by research area and learn more about each of the different research areas below.

Diabetes Research