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PNR/NR2E3 Antibody (2A12)

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Western Blot: PNR/NR2E3 Antibody (2A12) [H00010002-M01] - Analysis of NR2E3 expression in transfected 293T cell line by NR2E3 monoclonal antibody (M01), clone 2A12.Lane 1: NR2E3 transfected lysate(44.7 KDa).Lane 2: ...read more
Sandwich ELISA: PNR/NR2E3 Antibody (2A12) [H00010002-M01] - Detection limit for recombinant GST tagged NR2E3 is approximately 0.3ng/ml as a capture antibody.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
2A12
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

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PNR/NR2E3 Antibody (2A12) Summary

Immunogen
NR2E3 (AAH41421, 1 a.a. ~ 322 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MCPVDKAHRNQCQACRLKKCLQAGMNQDAVQNERQPRSTAQVHLDSMESNTESRPESLVAPPAPAGRSPRGPTPMSAARALGHHFMASLITAETCAKLEPEDADENIDVTSNDPEFPSSPYSSSSPCGLDSIHETSARLLFMAVKWAKNLPVFSSLPFRDQVILLEEAWSELFLLGAIQWSLPLDSCPLLAPPEASAAGGAQGRLTLASMETRVLQETISRFRALAVDPTEFACMKALVLFKPETRGLKDPEHVEALQDQSQVMLSQHSKAHHPSQPVRFGKLLLLLPSLRFITAERIELLFFRKTIGNTPMEKLLCDMFKN
Specificity
NR2E3 - nuclear receptor subfamily 2, group E, member 3
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
NR2E3
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Sandwich ELISA
  • Western Blot 1:500
Application Notes
Antibody reactive against recombinant protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
In 1x PBS, pH 7.4
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for PNR/NR2E3 Antibody (2A12)

  • NR2E3
  • Nuclear receptor subfamily 2 group E member 3
  • nuclear receptor subfamily 2, group E, member 3
  • photoreceptor-specific nuclear receptor
  • PNR
  • PNRESCS
  • rd7
  • Retina-specific nuclear receptor
  • RNR
  • RP37MGC49976

Background

This protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as well as in maintenance of proper cell function in adults. Members of this family are characterized by discrete domains that function in DNA and ligand binding. This gene encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. Defects in this gene are a cause of enhanced S cone syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol NR2E3
Entrez
OMIM
Uniprot