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Plasma Kallikrein/KLKB1 Antibody (SR2234)

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Western Blot: Plasma Kallikrein/KLKB1 Antibody (SR2234) [NBP3-21778] - Western blot analysis using NBP3-21778 in human plasma lysate.

Product Details

Summary
Reactivity Hu, RtSpecies Glossary
Applications WB, IHC, IP
Clone
SR2234
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Plasma Kallikrein/KLKB1 Antibody (SR2234) Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
A synthesized peptide derived from human Plasma Kallikrein/KLKB1 (Uniprot #: P03952)
Specificity
Detects endogenous levels of total Plasma Kallikrein/KLKB1
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
KLKB1
Purity
Affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50-1:200
  • Immunoprecipitation 1:50
  • Western Blot 1:500-1:2000
Theoretical MW
80 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, pH 7.4, 150mM NaCl, 50% glycerol.
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for Plasma Kallikrein/KLKB1 Antibody (SR2234)

  • EC 3.4.21
  • EC 3.4.21.34
  • Fletcher factor
  • kallikrein B, plasma (Fletcher factor) 1
  • kininogenin
  • KLK3plasma kallikrein
  • KLKB1
  • plasma kallikrein heavy chain
  • plasma kallikrein light chain
  • Plasma Kallikrein
  • Plasma Prekallikrein
  • PPK

Background

Plasma Kallikrein 1B is a serine proteinase of the S1 family It is secreted by the liver, kidney, adrenal gland and placenta. The zymogen is referred to as prekallikrein (PK) and is activated by Factor XIIa to an active two chain form, plasma kallikrein. In Fletcher syndrome plasma kallikrein is deficient, resulting in a prolonged partial thromboplastin time (PT).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol KLKB1