Plasma Kallikrein 1B is a serine proteinase of the S1 family It is secreted by the liver, kidney, adrenal gland and placenta. The zymogen is referred to as prekallikrein (PK) and is activated by Factor XIIa to an active two chain form, plasma kallikrein. In Fletcher syndrome plasma kallikrein is deficient, resulting in a prolonged partial thromboplastin time (PT).
![Immunohistochemistry Plasma Kallikrein/KLKB1 Antibody (736811) [Unconjugated]](http://images.novusbio.com/fullsize2/Plasma_Kallikrein_MAB2497_Immunohistochemistry_19035.jpg)
