Human Serpin A4/Kallistatin DuoSet ELISA, 15 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

The human serpin superfamily consists of at least 35 members that target not only serine proteases, but also selected cysteine proteases and non-protease proteins. Serpins bind the protease active site resulting in a major conformational rearrangement that traps the enzyme in a covalent acyl-enzyme intermediate. As protease inhibitors, serpins have an array of functions including regulating blood clotting, the complement pathway, extracellular matrix remodeling, and cell motility. They are also involved in activities that extend beyond their ability to inhibit proteases. For instance, they may also regulate blood pressure, angiogenesis, or act as storage/transport proteins.

We have publications tested in 1 confirmed species: Human.

Showing Publications 1 - 9 of 9.

Publications using DY1669	Applications	Species
Park, KH;Lee, KN;Oh, E;Im, EM; Inflammatory biomarkers in the cervicovaginal fluid to identify histologic chorioamnionitis and funisitis in women with preterm labor Cytokine 2023-09-01 [PMID: 37536223] (Human)		Human
N Arakawa, S Matsuyama, M Matsuoka, I Kitamura, K Miyashita, Y Kitagawa, K Imai, K Ogawa, T Maeda, Y Saito, C Hasegawa Serum stratifin and presepsin as candidate biomarkers for early detection of COVID-19 disease progression Journal of pharmacological sciences, 2022-06-13;150(1):21-30. 2022-06-13 [PMID: 35926945] (Human)		Human
J Huang, Y Mao, Q Li, H Hong, N Tang, X Kang, Y Huang, J Liu, Q Gong, Y Yao, L Li Kallistatin prevents ovarian hyperstimulation syndrome by regulating vascular leakage Journal of Cellular and Molecular Medicine, 2022-07-21;26(16):4613-4623. 2022-07-21 [PMID: 35866203] (Human)		Human
KN Lee, KH Park, YM Kim, I Cho, TE Kim Prediction of emergency cerclage outcomes in women with cervical insufficiency: The role of inflammatory, angiogenic, and extracellular matrix-related proteins in amniotic fluid PLoS ONE, 2022-05-10;17(5):e0268291. 2022-05-10 [PMID: 35536791] (Human)		Human
SM Krishna, J Li, Y Wang, CS Moran, A Trollope, P Huynh, R Jose, E Biros, J Ma, J Golledge Kallistatin limits abdominal aortic aneurysm by attenuating generation of reactive oxygen species and apoptosis Scientific Reports, 2021-08-31;11(1):17451. 2021-08-31 [PMID: 34465809] (Human)		Human
Yiu W, Wong D, Wu H, Li R, Yam I, Chan L, Leung J, Lan H, Lai K, Tang S Kallistatin protects against diabetic nephropathy in db/db mice by suppressing AGE-RAGE-induced oxidative stress. Kidney Int, 2016-02-01;0(0):. 2016-02-01 [PMID: 26536000] (Human)		Human
Tuo J, Wang Y, Cheng R, Li Y, Chen M, Qiu F, Qian H, Shen D, Penalva R, Xu H, Ma J, Chan C Wnt signaling in age-related macular degeneration: human macular tissue and mouse model. J Transl Med, 2015-10-17;13(0):330. 2015-10-17 [PMID: 26476672] (Human)		Human
McBride J, Jenkins A, Liu X, Zhang B, Lee K, Berry W, Janknecht R, Griffin C, Aston C, Lyons T, Tomasek J, Ma J Elevated circulation levels of an antiangiogenic SERPIN in patients with diabetic microvascular complications impair wound healing through suppression of Wnt signaling. J Invest Dermatol, 2014-01-24;134(6):1725-34. 2014-01-24 [PMID: 24463424] (Human)		Human
Liu , Xiaochen, Zhang , Bin, McBride , Jeffrey, Zhou , Kevin, Lee , Kyungwon, Zhou , Yueping, Liu , Zuguo, Ma , Jian-xin Antiangiogenic and antineuroinflammatory effects of kallistatin through interactions with the canonical Wnt pathway. Diabetes, 2013-07-24;62(12):4228-38. 2013-07-24 [PMID: 23884893] (Human)		Human

Array DY1669

• Serpin A4/Kallistatin Antibodies
• Serpin A4/Kallistatin Protein
• Serpin A4/Kallistatin ELISA
• Serpin A4/Kallistatin Proteins and Enzyme