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PLA2R1 Antibody (12-6-5) [Janelia Fluor® 669]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, Flow, ICC/IF, IHC, CyTOF-ready
Clone
12-6-5
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 669

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-50248AF350
Alexa Fluor 405
NBP2-50248AF405
Alexa Fluor 488
NBP2-50248AF488
Alexa Fluor 532
NBP2-50248AF532
Alexa Fluor 594
NBP2-50248AF594
Alexa Fluor 647
NBP2-50248AF647
Alexa Fluor 700
NBP2-50248AF700
Alexa Fluor 750
NBP2-50248AF750
Allophycocyanin
NBP2-50248APC
Allophycocyanin/Cy7
NBP2-50248APCCY7
Biotin
NBP2-50248B
CoraFluor 1
NBP2-50248CL1
DyLight 350
NBP2-50248UV
DyLight 405
NBP2-50248V
DyLight 488
NBP2-50248G
DyLight 550
NBP2-50248R
DyLight 594
NBP2-50248DL594
DyLight 650
NBP2-50248C
DyLight 680
NBP2-50248FR
DyLight 755
NBP2-50248IR
FITC
NBP2-50248F
HRP
NBP2-50248H
Janelia Fluor 525
NBP2-50248JF525
Janelia Fluor 549
NBP2-50248JF549
Janelia Fluor 585
NBP2-50248JF585
Janelia Fluor 635
NBP2-50248JF635
Janelia Fluor 646
NBP2-50248JF646
PE
NBP2-50248PE
PE/Atto594
NBP2-50248PEATT594
PE/Cy5.5
NBP2-50248PECY55
PE/Cy7
NBP2-50248PECY7
PerCP
NBP2-50248PCP
Unconjugated
NBP2-50248
mFluor Violet 450 SE
NBP2-50248MFV450
mFluor Violet 500 SE
NBP2-50248MFV500
mFluor Violet 610 SE
NBP2-50248MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-50248
BSA Free
NBP2-50248
Azide and BSA Free
NBP2-80912
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PLA2R1 Antibody (12-6-5) [Janelia Fluor® 669] Summary

Immunogen
Human PLA2R extracellular sequence N-C3 (containing domains N-terminal Cysteine rich-FibII-CTLD1-CTLD2-CTLD3). Genbank acc no. U17033; amino acids 20-663 Recombinant protein expressed in HEK 293-EBNA-1 cells
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
PLA2R1
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • ELISA
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for PLA2R1 Antibody (12-6-5) [Janelia Fluor® 669]

  • 180 kDa secretory phospholipase A2 receptor
  • CLEC13C
  • CLEC13CC-type lectin domain family 13 member C
  • phospholipase A2 receptor 1, 180kDa
  • PLA2G1R
  • PLA2IR
  • PLA2R1
  • PLA2-RM-type receptor
  • PLA2Rphospholipase A2 receptor 1, 180kD
  • secretory phospholipase A2 receptor

Background

Secretory phospholipases A2 (PLA2s) have been purified from a variety of mammalian tissues as well as from insect and snake venoms. The prototype group I PLA2, the pancreatic PLA2 (PLA2G1B; MIM 172410), is involved in digestion, smooth muscle contraction, and cell proliferation. The prototype group II PLA2, the inflammatory-type PLA2 (PLA2G2A; MIM 172411), is involved in inflammatory conditions and is upregulated by proinflammatory cytokines like tumor necrosis factor (TNF; MIM 191160) and interleukin-1 (e.g., IL1B; MIM 147720). Differential toxicity of snake venom Pla2 appears to be linked to a variety of high-affinity receptors in different organs (Ancian et al., 1995 (PubMed 7721806)).(supplied by OMIM)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PLA2R1