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PINCH1/LIMS1 Antibody

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Immunohistochemistry-Paraffin: PINCH1/LIMS1 Antibody [NBP2-46851] - Staining of human adrenal gland shows cytoplasmic positivity in glandular cells.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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PINCH1/LIMS1 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: MAFSGRARPCIIPENEEIPRAALNTVHEANGTEDERAVSKLQRRHSDVKVY
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
LIMS1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
PINCH1/LIMS1 Recombinant Protein Antigen (NBP2-46851PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (84%), Rat (80%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for PINCH1/LIMS1 Antibody

  • LIM and senescent cell antigen-like domains 1
  • LIM and senescent cell antigen-like-containing domain protein 1
  • LIMS1
  • PINCH1
  • PINCH-1
  • PINCHPINCH1Particularly interesting new Cys-His protein 1
  • Renal carcinoma antigen NY-REN-48

Background

The protein encoded by the LIMS1 gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol LIMS1
Uniprot