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PINCH1/LIMS1 Antibody

Images

 
Western Blot: PINCH1/LIMS1 Antibody [NBP2-19354] - A: Hela.
Immunohistochemistry-Paraffin: PINCH1/LIMS1 Antibody [NBP2-19354] - Analysis of paraffin-embedded BT474 xenograft, using antibody at 1:100 dilution.

Product Details

Summary
Reactivity Hu, XpSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

PINCH1/LIMS1 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human PINCH1/LIMS1. The exact sequence is proprietary.
Predicted Species
Xenopus (98%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
LIMS1
Purity
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 10 - 1:500
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:500-1:3000
Theoretical MW
37 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol
Preservative
0.01% Thimerosal
Purity
Antigen Affinity-purified

Alternate Names for PINCH1/LIMS1 Antibody

  • LIM and senescent cell antigen-like domains 1
  • LIM and senescent cell antigen-like-containing domain protein 1
  • LIMS1
  • PINCH1
  • PINCH-1
  • PINCHPINCH1Particularly interesting new Cys-His protein 1
  • Renal carcinoma antigen NY-REN-48

Background

The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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Bioinformatics

Gene Symbol LIMS1
Uniprot