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Pin1 Antibody (S01-7G8)

Images

 
Western Blot: Pin1 Antibody (S01-7G8) [NBP3-15076] - Western blot detection of Pin1 in Jurkat, Rat Brain, C6, CHO-K1, Hela cell lysates using Pin1 Rabbit mAb (1:1000 diluted). Predicted band size: 18kDa. Observed band ...read more
Immunohistochemistry-Paraffin: Pin1 Antibody (S01-7G8) [NBP3-15076] - Immunohistochemistry of Pin1 in paraffin-embedded Human breast cancer tissue using Pin1 Rabbit mAb at dilution 1/50

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC
Clone
S01-7G8
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Pin1 Antibody (S01-7G8) Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
Recombinant protein of mouse Pin1 (Uniprot#: Q13526)
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
PIN1
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1/20
  • Immunohistochemistry-Paraffin
  • Western Blot 1/1000
Theoretical MW
18 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA
Preservative
0.01% Sodium Azide
Purity
Affinity purified

Alternate Names for Pin1 Antibody (S01-7G8)

  • dod
  • EC 5.2.1.8
  • peptidylprolyl cis/trans isomerase, NIMA-interacting 1
  • peptidyl-prolyl cis/trans isomerase, NIMA-interacting
  • peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
  • Peptidyl-prolyl cis-trans isomerase Pin1
  • Pin1
  • PPIase Pin1
  • prolyl isomerase
  • protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1
  • protein (peptidylprolyl cis/trans isomerase) NIMA-interacting 1
  • Rotamase Pin1
  • UBL5

Background

Pin-1 is a the peptidylprolyl cis/trans isomerase enzyme which is responsible, as its name suggests, for flipping the proline ring from the cis to the trans conformation. This enzyme is heavily upregulated in tumor cells, so that antibodies to this protein can be used as tumor markers. Pin-1 protein is concentrated in the nucleus in small punctate structures and is particularly obvious in tumor cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol PIN1