PIM2 Antibody

PIM2 belongs to a family of cytoplasmic serine/threonine protein kinases that consists of two other members, PIM1 and PIM3. Expression of this protein is regulated by hematopoietic cytokines. PIM2 is most abundantly expressed in hematopoietic tissues, spleen, thymus, and peripheral blood leukocytes, as well as in testis, small intestine, and colon. It is also highly expressed in human leukemic and lymphoma cell lines. The gene is also expressed in primary spermatocytes. The results suggest a role for PIM2 in proliferating cells as well as during meiosis. PIM2 is thought to be a mediator of p53 mediated apoptosis inhibition by interleukin 3, which supports its role in the formation of various tumours including lymphomas.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publication using NBP2-26115	Applications	Species
Hammerman PS, Fox CJ, Cinalli RM et al. Lymphocyte transformation by Pim-2 is dependent on nuclear factor-kappaBactivation. Cancer Res 2004-11-15 [PMID: 15548703]

Array NBP2-26115

• PIM2 Antibodies
• PIM2 ELISA Kits
• PIM2 Lysate
• PIM2 Protein