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Phospholamban [p Ser16] Antibody (HL1710) - Azide and BSA Free

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Western Blot: Phospholamban [p Ser16] Antibody (HL1710) - Azide and BSA Free [NBP3-25600] - Untreated (-) and treated (+) Mouse tissue extract (50 ug) were separated by 15% SDS-PAGE, and the membrane was blotted with ...read more

Product Details

Summary
Reactivity Mu, Hu, Rt, Po, Bv, Ca, Rb, RMSpecies Glossary
Applications WB
Clone
HL1710
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated
Format
Azide and BSA Free

Order Details

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Phospholamban [p Ser16] Antibody (HL1710) - Azide and BSA Free Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
Carrier-protein conjugated synthetic peptide surrounding phospho Ser16 of human Phospholamban . The exact sequence is proprietary
Modification
p Ser16
Predicted Species
Human (100%), Rat (100%), Porcine (100%), Bovine (100%), Rabbit (100%), Rhesus Macaque (100%), Canine (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
PLN
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
No Preservative
Purity
Protein A purified

Alternate Names for Phospholamban [p Ser16] Antibody (HL1710) - Azide and BSA Free

  • CMD1PPLBcardiac phospholamban
  • phospholamban

Background

Phospholamban (PLB) is a 52 amino acid phosphoprotein which regulates the calcium pump of cardiac sarcoplasmic reticulum (SR). PLB is an oligomer of five identical subunits each having a cytoplasmic and transmembrane domain. The cytoplasmic domain (residues 1-25) contains the phosphorylation sites and is highly basic and readily cleaved by proteases; whereas the transmembrane domain (residues 25-52) is mostly hydrophobic, protease resistant and stabilizes the pentamer. Following adrenergic stimulation of cardiac muscle, PLB is phosphorylated at Ser16 and at Thr17 which is correlated with stimulation of calcium transport activity across the SR membrane and relaxation of cardiac fibers.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for Phospholamban Antibody (NBP3-25600) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol PLN