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PDGF-D/SCDGFB Antibody [Unconjugated]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
LYOPH

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PDGF-D/SCDGFB Antibody [Unconjugated] Summary

Immunogen
E. coli-derived recombinant human PDGF-D
Asp253-Arg370
Accession # Q9GZP0
Specificity
Detects human PDGF-D in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human (rh) PDGF-AA, rhPDGF-AB and rhPDGF-BB is observed.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
PDGFD
Purity Statement
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 5-15 ug/mL
  • Western Blot 0.1 ug/mL
Publications
Read Publications using
AF1159 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for PDGF-D/SCDGFB Antibody [Unconjugated]

  • IEGFMSTP036
  • Iris-expressed growth factor
  • PDGFD
  • PDGF-D
  • platelet derived growth factor D
  • SCDGF-BMGC26867
  • SCDGFBplatelet-derived growth factor D
  • spinal cord derived growth factor B
  • Spinal cord-derived growth factor B
  • spinal cord-derived growth factor-B

Background

PDGF-D, also named spinal cord-derived growth factor B (SCDGF-B) is a member of the PDGF/VEGF family.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for PDGF-D/SCDGFB Antibody (AF1159)(7)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 6 applications: IHC, IHC-Fr, Immunohistochemistry, Immunoprecipitation, Neutralization, Western Blot.


Filter By Application
IHC
(2)
IHC-Fr
(1)
Immunohistochemistry
(1)
Immunoprecipitation
(1)
Neutralization
(1)
Western Blot
(2)
All Applications
Filter By Species
Human
(5)
All Species
Showing Publications 1 - 7 of 7.
Publications using AF1159 Applications Species
T Akiyama, T Yasuda, T Uchihara, N Yasuda-Yos, BJY Tan, A Yonemura, T Semba, J Yamasaki, Y Komohara, K Ohnishi, F Wei, L Fu, J Zhang, F Kitamura, K Yamashita, K Eto, S Iwagami, H Tsukamoto, T Umemoto, M Masuda, O Nagano, Y Satou, H Saya, P Tan, H Baba, T Ishimoto Stromal reprogramming through dual PDGFRalpha/beta blockade boosts the efficacy of anti-PD-1 immunotherapy in fibrotic tumors Cancer Research, 2023-03-02;0(0):. 2023-03-02 [PMID: 36543251] (Immunohistochemistry, Human) Immunohistochemistry Human
Y Nordby, E Richardsen, M Rakaee, N Ness, T Donnem, HR Patel, LT Busund, RM Bremnes, S Andersen High expression of PDGFR-? in prostate cancer stroma is independently associated with clinical and biochemical prostate cancer recurrence Sci Rep, 2017-02-24;7(0):43378. 2017-02-24 [PMID: 28233816] (IHC, Human) IHC Human
Huang W, Kim H Dynamic regulation of platelet-derived growth factor D (PDGF-D) activity and extracellular spatial distribution by matriptase-mediated proteolysis. J Biol Chem, 2015-02-12;290(14):9162-70. 2015-02-12 [PMID: 25678707] (Immunoprecipitation, Human) Immunoprecipitation Human
Jie Ding, Xiao-Mao Li, Sui-Ling Liu, Yu Zhang, Tian Li Overexpression of Platelet-derived Growth Factor-D as a Poor Prognosticator in Endometrial Cancer Asian Pacific Journal of Cancer Prevention 5/30/2014 [PMID: 24870786]
Thomas Karsten Kilvaer, Andrej Valkov, Sveinung W. Sorbye, Tom Donnem, Eivind Smeland, Roy Martin Bremnes et al. Platelet-Derived Growth Factors in Non-GIST Soft-Tissue Sarcomas Identify a Subgroup of Patients with Wide Resection Margins and Poor Disease-Specific Survival Sarcoma 1/23/2011 [PMID: 21331156]
Wagsater D, Zhu C, Bjorck HM, Eriksson P Effects of PDGF-C and PDGF-D on monocyte migration and MMP-2 and MMP-9 expression. Atherosclerosis, 2008-05-22;202(2):415-23. 2008-05-22 [PMID: 18573494] (IHC-Fr, Neutralization, Western Blot, Human) IHC-Fr, Neutralization, Western Blot Human
Pohlers D, Huber R, Ukena B, Kinne RW Expression of platelet-derived growth factors C and D in the synovial membrane of patients with rheumatoid arthritis and osteoarthritis. Arthritis Rheum., 2006-03-01;54(3):788-94. 2006-03-01 [PMID: 16508943] (IHC, Western Blot, Human) IHC, Western Blot Human

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Bioinformatics

Gene Symbol PDGFD
Uniprot