Novus Biologicals products are now on bio-techne.com

PDGF-C Antibody (5F12) [Janelia Fluor® 669]

Images

 
There are currently no images for PDGF-C Antibody (NBP2-21956JF669).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, B/N
Clone
5F12
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 669

Order Details

Novus Biologicals is part of Bio-Techne

Shop this product on bio-techne.com

PDGF-C Antibody (5F12) [Janelia Fluor® 669] Summary

Immunogen
Human recombinant PDGF-C
Isotype
IgG2
Clonality
Monoclonal
Host
Mouse
Gene
PDGFC
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Block/Neutralize
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for PDGF-C Antibody (5F12) [Janelia Fluor® 669]

  • FALLOTEIN
  • PDGFC
  • PDGF-C
  • platelet derived growth factor C
  • platelet-derived growth factor C
  • SCDGFSpinal cord-derived growth factor
  • secretory growth factor-like protein
  • VEGF-E

Background

PDGFC, also known as Platelet-derived growth factor C, has 3 isoforms, a 345 amino acid isoform that is 39 kDa, a 282 amino acid isoform that is 32 kDa and a 167 amino acid isoform that is 19 kDa, expressed in the fallopian tube, vascular smooth muscle cells in kidney, breast and colon and in visceral smooth muscle of the gastrointestinal tract and retinal pigment epithelia; plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis, wound healing, represents potent mitogen for cells of mesenchymal origin, induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis, can initiate events that lead to a mesangial proliferative glomerulonephritis, including influx of monocytes and macrophages and production of extracellular matrix. This protein is being studied for its involvement in mesangial proliferative glomerulonephritis, proliferative glomerulonephritis, glomerulonephritis, brain cancer, prostate carcinoma, nephropathy, prostatitis, prostate cancer, atherosclerosis, retinitis, melanoma, and carcinoma. The protein has been linked to the cytoskeleton remodeling role of PDGFs in cell migration, development PDGF signaling via MAPK cascades, release of novel PDGFs as latent factors, signal transduction, signaling by PD, focal adhesion, gap junction, regulation of actin cytoskeleton, prostate cancer, and melanoma GF pathways where it interacts with PDGFRB, PDGFRA, PLAT, PLAU, PLAUR, EGFR, ERBB2, FGFR1, FLT1, and FLT4 proteins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

DVE00
Species: Hu
Applications: ELISA
1159-SB
Species: Hu
Applications: BA
221-AA
Species: Hu
Applications: BA
NBP1-58279
Species: Hu
Applications: ICC/IF, IHC, IHC-P, KD, WB
AF321
Species: Hu
Applications: Block, CyTOF-ready, Flow, IHC, WB
DPG00
Species: Hu
Applications: ELISA
AF1042
Species: Mu
Applications: Dual ISH-IHC, IHC, WB
AF1062
Species: Mu
Applications: Flow, IHC, Neut, WB
AF644
Species: Mu
Applications: CyTOF-ready, Dual ISH-IHC, Flow, IHC, Neut, WB
DVEC00
Species: Hu
Applications: ELISA
233-FB
Species: Hu
Applications: BA
NBP2-22203
Species: Hu, Pm, Mu, Rt
Applications: ELISA, Flow, ICC/IF, IHC, IHC-P, WB
AF1230
Species: Hu, Mu, Rt
Applications: IHC, KO, WB
AF743
Species: Mu
Applications: CyTOF-ready, Flow, WB
AF887
Species: Hu, Mu, Rt
Applications: CyTOF-ready, IHC, ICFlow, Simple Western, WB
NBP2-21956JF669
Species: Hu
Applications: WB, B/N

Publications for PDGF-C Antibody (NBP2-21956JF669) (0)

There are no publications for PDGF-C Antibody (NBP2-21956JF669).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for PDGF-C Antibody (NBP2-21956JF669) (0)

There are no reviews for PDGF-C Antibody (NBP2-21956JF669). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for PDGF-C Antibody (NBP2-21956JF669) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional PDGF-C Products

Research Areas for PDGF-C Antibody (NBP2-21956JF669)

Find related products by research area.

Blogs on PDGF-C

There are no specific blogs for PDGF-C, but you can read our latest blog posts.
Read our latest blog and use the new citation tool on bio-techne.com

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our PDGF-C Antibody (5F12) [Janelia Fluor® 669] and receive a gift card or discount.

Bioinformatics

Gene Symbol PDGFC