Western Blot: PD-ECGF/Thymidine Phosphorylase Antibody [NBP1-84916] - Analysis in human cell line CAPAN-2.
Orthogonal Strategies: Immunohistochemistry-Paraffin: PD-ECGF/Thymidine Phosphorylase Antibody [NBP1-84916] - Staining in human lymph node and skeletal muscle tissues . Corresponding TYMP RNA-seq data are ...read more
Immunohistochemistry-Paraffin: PD-ECGF/Thymidine Phosphorylase Antibody [NBP1-84916] - Staining of human lymph node shows moderate cytoplasmic positivity in lymphoid cells.
Immunohistochemistry-Paraffin: PD-ECGF/Thymidine Phosphorylase Antibody [NBP1-84916] - Staining of human lung shows moderate cytoplasmic positivity in macrophages.
Immunohistochemistry-Paraffin: PD-ECGF/Thymidine Phosphorylase Antibody [NBP1-84916] - Staining of human small intestine shows moderate cytoplasmic positivity in lymphoid cells.
Immunohistochemistry-Paraffin: PD-ECGF/Thymidine Phosphorylase Antibody [NBP1-84916] - Staining of human skeletal muscle shows no positivity in myocytes as expected.
This antibody was developed against Recombinant Protein corresponding to amino acids: EGSQGLPDPSPEPKQLPELIRMKRDGGRLSEADIRGFVAAVVNGSAQGAQIGAMLMAIRLRGMDLEETSVLTQALAQSGQQLEWPEAWRQQLVDKHSTGGVGDKVSLVLAPALAACGCKVPMISG
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TYMP
Purity
Immunogen affinity purified
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IHC reported in scientific literature (PMID: 26623038). For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Theoretical MW
50 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Thymidine Phosphorylase encodes an angiogenic factor which promotes angiogenesis in vivo and stimulates the in vitro growth of a variety of endothelial cells. It has a highly restricted target cell specificity acting only on endothelial cells. Mutations in this gene have been associated with mitochondrial neurogastrointestinal encephalomyopathy. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq]
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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