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P2X7/P2RX7 Antibody (CL11508)

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Analysis in human cell line SK-MEL-30.
Analysis in human cell line SK-MEL-30.
Staining of human Cerebral cortex shows moderate positivity in neuronal processes in neuropil.
Staining of human Cerebellum shows strong positivity in neuronal processes in neuropil.
Staining of human Endometrium shows strong membranous positivity in glandular cells.
Staining of human Kidney shows strong membranous positivity in cells in glomeruli and tubules.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, IHC
Clone
CL11508
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

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P2X7/P2RX7 Antibody (CL11508) Summary

Immunogen
This antibody was developed against a Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence of Q99572. Actual immunogen sequence is proprietary.
Predicted Species
Mouse (100%). Backed by our 100% Guarantee.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
P2RX7
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:500- 1:1000
  • Immunohistochemistry-Paraffin 1:500- 1:1000
  • Western Blot 1 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Reactivity Notes

Rat (85%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, pH 7.2, 40% glycerol
Preservative
0.02% Sodium Azide
Purity
Protein A purified

Alternate Names for P2X7/P2RX7 Antibody (CL11508)

  • ATP receptor
  • MGC20089
  • P2RX7
  • P2X purinoceptor 7
  • P2X7
  • P2X7P2X7 receptor
  • P2X7R
  • P2Z receptor
  • purinergic receptor P2X, ligand-gated ion channel, 7
  • purinergic receptor P2X7 variant A
  • Purinergic receptor

Background

FUNCTION: Receptor for ATP that acts as a ligand gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells.; Subcellular location: Membrane; Multi-pass membrane protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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NBP3-21196
P2X7/P2RX7 Antibody (CL11508)
Species: Hu, Mu
Applications: WB, IHC

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Bioinformatics

Gene Symbol P2RX7