ODF2 Antibody (1A1)

This product is produced by and distributed for Abnova, a company based in Taiwan.

The outer dense fibers are cytoskeletal structures that surround the axoneme in the middle piece and principal piece of the sperm tail. The fibers function in maintaining the elastic structure and recoil of the sperm tail as well as in protecting the tail from shear forces during epididymal transport and ejaculation. Defects in the outer dense fibers lead to abnormal sperm morphology and infertility. This gene encodes one of the major outer dense fiber proteins. Multiple protein isoforms are encoded by transcript variants of this gene; however, not all isoforms and variants have been fully described.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 3 confirmed species: Human, Mouse, C. elegans.

We have publications tested in 3 applications: ICC/IF, IF/IHC, WB.

Showing Publications 1 - 10 of 14. Show All 14 Publications. Collapse Publications.

Publications using H00004957-M01	Applications	Species
Ching K, Wang JT, Stearns T Long-range migration of centrioles to the apical surface of the olfactory epithelium eLife 2022-04-14 [PMID: 35420544] (ICC/IF, Mouse)	ICC/IF	Mouse
Yingyi Z, Jielu H, Mariana T et al. FBF1 deficiency promotes beiging and healthy expansion of white adipose tissue. Cell Rep. 2021-08-03 [PMID: 34348145]
H Yan, C Chen, H Chen, H Hong, Y Huang, K Ling, J Hu, Q Wei TALPID3 and ANKRD26 selectively orchestrate FBF1 localization and cilia gating Nat Commun, 2020-05-04;11(1):2196. 2020-05-04 [PMID: 32366837]
Kodani A, Kenny C, Lai A et al. Posterior Neocortex-Specific Regulation of Neuronal Migration by CEP85L Identifies Maternal Centriole-Dependent Activation of CDK5. Neuron. 2020-02-13 [PMID: 32097629]
Eunji J, Tae-Ik C, Ji-Eun L et al. ESCRT subunit CHMP4B localizes to primary cilia and is required for the structural integrity of the ciliary membrane. FASEB J. 2019-11-29 [PMID: 31914703]
Hiraiwa T, Nakai Y, Yamada T et al. Quantitative analysis of sensitivity to a Wnt3a gradient in determination of the pole-to-pole axis of mitotic cells by using a microfluidic device. FEBS Open Bio 2018-09-16 [PMID: 30524943] (ICC/IF, Human)	ICC/IF	Human
Mazo G, Soplop N, Wang WJ et al. Spatial Control of Primary Ciliogenesis by Subdistal Appendages Alters Sensation-Associated Properties of Cilia Developmental Cell 2016-11-01 [PMID: 27818179]
Xu Q, Zhang Y, Wei Q et al. Phosphatidylinositol phosphate kinase PIPKIgamma and phosphatase INPP5E coordinate initiation of ciliogenesis. Nat Commun 2016-02-26 [PMID: 26916822] (WB)	WB
Alby C, Piquand K, Huber C et al. Mutations in KIAA0586 Cause Lethal Ciliopathies Ranging from a Hydrolethalus Phenotype to Short-Rib Polydactyly Syndrome. Am J Hum Genet 2015-08-06 [PMID: 26166481]
Failler M, Gee HY, Krug P et al. Mutations of CEP83 Cause Infantile Nephronophthisis and Intellectual Disability. Am J Hum Genet 2014-06-05 [PMID: 24882706] (ICC/IF, Human)	ICC/IF	Human
Xu Q, Zhang Y, Xiong X et al. Type Igamma phosphatidylinositol phosphate kinase targets to the centrosome and restrains centriole duplication. J Cell Sci. 2014-01-16 [PMID: 24434581]
Wei Q, Xu Q, Zhang Y et al. Transition fibre protein FBF1 is required for the ciliary entry of assembled intraflagellar transport complexes. Nat Commun. 2013-11-15 [PMID: 24231678] (IF/IHC, ICC/IF, C. elegans)	IF/IHC, ICC/IF	C. elegans
Tanos BE, Yang HJ, Soni R et al. Centriole distal appendages promote membrane docking, leading to cilia initiation. Genes Dev 2013-01-15 [PMID: 23348840] (ICC/IF, Human)	ICC/IF	Human
Izumi H, Kaneko Y. Evidence of asymmetric cell division and centrosome inheritance in human neuroblastoma cells Proc Natl Acad Sci 2012-10-11 [PMID: 23064640] (ICC/IF, Human)	ICC/IF	Human
Show All 14 Publications. Collapse Publications.

Images	Ratings	Applications	Species	Date	Details
Enlarge	5 reviewed by: Verified Customer	IF	Human	04/09/2019	View Summary Application Immunofluorescence Sample Tested hTERT RPE-1 cell line from ATCC,RPE1 cells Species Human Lot G9131-1A1 Comments Comments Fix by cold MEOH for 10 mins. Block with 3% BSA for 0.5 hours at room temperature. Dilute the ab at 1:100 in 3% BSA and incubate with cells for 2 hours at room temperature.
	5 reviewed by: Verified Customer	ICC	Human	08/25/2010	View Summary Application Immunocytochemistry Sample Tested hTERT RPE-1 cell line from ATCC Species Human

Array H00004957-M01

• ODF2 Antibodies
• ODF2 Proteins