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NKG2E/KLRC3 Antibody [Janelia Fluor® 585]

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Summary
Product Discontinued
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    • Catalog Number
      NBP2-99155JF585
    • Availability
      Product Discontinued

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NKG2E/KLRC3 Antibody [Janelia Fluor® 585] Summary

Immunogen
Produced in rabbits immunized with a synthetic peptide corresponding to the N-terminus of the Human NKG2E/KLRC3
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
KLRC3
Purity
Antigen and protein A Affinity-purified
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Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Antigen and protein A Affinity-purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for NKG2E/KLRC3 Antibody [Janelia Fluor® 585]

  • killer cell lectin-like receptor subfamily C, member 3
  • NK cell receptor E
  • NKG2-E type II integral membrane protein
  • NKG2E
  • NKG2-E-activating NK receptor
  • NKG2ENKG2-E

Background

KLRC3 codes for a protein that works as a receptor for the recognition of MHC molecules by natural killers, and in some cases cytotoxic T-cells. KLRC3 is a gene made up of two isoforms, measuring 240 and 257 amino acids in length, and weighing approximately 27 and 29 kDa respectively. Studies have been done on diseases and disorders relating to this gene including monkeypox. KLRC3 has also been shown to have interactions with KLRD1, TYROBP, HLA-A, and HLA-C in pathways such as the antigen processing and natural killer cell mediated cytotoxicity pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Harnessing Natural Killer Cell Activity for Anti-Tumor Immunotherapy
By Victoria Osinski, PhDWhat’s “Natural” About Natural Killer (NK) Cells?For immunologists, the term cytotoxicity often conjures up images of an army of antigen specific CD8+ T cells deploying to ...  Read full blog post.
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Bioinformatics

Gene Symbol KLRC3