Home » Neutrophil Elastase/ELA2 » Neutrophil Elastase/ELA2 Antibodies » Neutrophil Elastase/ELA2 Antibody (ELA10-101.5 (39A)) [DyLight 405]
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Neutrophil Elastase/ELA2 Antibody (ELA10-101.5 (39A)) [DyLight 405]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, Flow
Clone
ELA10-101.5 (39A)
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 405

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB100-64392AF350
Alexa Fluor 405
NB100-64392AF405
Alexa Fluor 488
NB100-64392AF488
Alexa Fluor 532
NB100-64392AF532
Alexa Fluor 594
NB100-64392AF594
Alexa Fluor 647
NB100-64392AF647
Alexa Fluor 700
NB100-64392AF700
Alexa Fluor 750
NB100-64392AF750
Allophycocyanin
NB100-64392APC
CoraFluor 1
NB100-64392CL1
DyLight 350
NB100-64392UV
DyLight 488
NB100-64392G
DyLight 550
NB100-64392R
DyLight 594
NB100-64392DL594
DyLight 650
NB100-64392C
DyLight 680
NB100-64392FR
DyLight 755
NB100-64392IR
Janelia Fluor 525
NB100-64392JF525
Janelia Fluor 549
NB100-64392JF549
Janelia Fluor 646
NB100-64392JF646
Janelia Fluor 669
NB100-64392JF669
PE
NB100-64392PE
PerCP
NB100-64392PCP
Unconjugated
NB100-64392
mFluor Violet 450 SE
NB100-64392MFV450
mFluor Violet 500 SE
NB100-64392MFV500
mFluor Violet 610 SE
NB100-64392MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NB100-64392
BSA Free
NB100-64392
BSA Free
NB100-64392-0.025mg
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Neutrophil Elastase/ELA2 Antibody (ELA10-101.5 (39A)) [DyLight 405] Summary

Description
This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
Immunogen
Elastase from human neutrophils
Localization
Secreted
Specificity
NB100-64392 is specific for human neutrophil elastase.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
ELANE
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry

Reactivity Notes

Not yet tested in other species.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Neutrophil Elastase/ELA2 Antibody (ELA10-101.5 (39A)) [DyLight 405]

  • Bone marrow serine protease
  • EC 3.4.21
  • EC 3.4.21.37
  • ELA2
  • ELA2granulocyte-derived elastase
  • ELANE
  • elastase 2, neutrophil
  • elastase, neutrophil expressed
  • Elastase-2
  • GE
  • HLEelastase-2
  • HNE
  • Human leukocyte elastase
  • Leukocyte Elastase
  • Medullasin
  • NE
  • Neutrophil Elastase
  • PMN elastase
  • PMN-E
  • polymorphonuclear elastase
  • SCN1

Background

The ELANE gene (commonly known as neutrophil elastase) encodes a 267 amino acid long, 28 kDA neutrophil elastase protein that functions in regulation of natural killer cells, monocytes, and graulocytes. ELANE is involved in activation of proMMP8, cell adhesion cell-matrix glycoconjugates, selected targets of C/EBPbeta, degradation of the extracellular matrix and collagen, and amb2 integrin signaling. It interacts with various genes GZMB, LRP1, SERPINF2, SERPING1, and SERPINA1. Elane has been linked to cystic fibrosis, asthma, pneumonia, alzheimer's disease, neutropenia, cutis laxia, leg ulcers, wegener's granulomatosis, bronchitis, adult respiratory distress syndrome, and vascular diseases.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ELANE