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NEIL1 Antibody (OTI1D1)

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Western Blot: NEIL1 Antibody (1D1) [NBP2-45857] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NEIL1.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clone
OTI1D1
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1 mg/ml

NEIL1 Antibody (OTI1D1) Summary

Immunogen
Human recombinant protein fragment corresponding to amino acids 186-390 of human NEIL1 (NP_078884) produced in E.coli.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
NEIL1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:200
Theoretical MW
43.5 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for NEIL1 Antibody (OTI1D1)

  • DNA-(apurinic or apyrimidinic site) lyase Neil1
  • EC 3.2.2.-
  • EC 4.2.99.18
  • endonuclease 8-like 1
  • endonuclease VIII
  • Endonuclease VIII-like 1
  • FLJ22402
  • FPG1DNA glycosylase/AP lyase Neil1
  • hFPG1
  • NEH1
  • nei endonuclease VIII-like 1 (E. coli)
  • Nei homolog 1
  • NEI1
  • Nei-like protein 1

Background

NEIL1 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol NEIL1