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NCF1 Antibody [Alexa Fluor® 488]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Alexa Fluor 488

Order Details

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NCF1 Antibody [Alexa Fluor® 488] Summary

Immunogen
Produced in rabbits immunized with E. coli-derived Human NCF1 fragment.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
NCF1
Purity
Antigen and protein A Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Antigen and protein A Affinity-purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for NCF1 Antibody [Alexa Fluor® 488]

  • 47 kDa neutrophil oxidase factor
  • FLJ79451
  • NADPH oxidase organizer 2
  • NCF-1
  • NCF1A
  • neutrophil cytosol factor 1,47 kDa autosomal chronic granulomatous disease protein
  • neutrophil cytosolic factor 1 (47kD, chronic granulomatous disease, autosomal1)
  • neutrophil cytosolic factor 1
  • neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1)
  • Neutrophil NADPH oxidase factor 1
  • Nox organizer 2
  • NOXO2NCF-47K
  • Nox-organizing protein 2
  • p47phox
  • SH3 and PX domain-containing protein 1A
  • SH3PXD1Ap47-phox

Background

NCF1, along with NCF2 and a membrane bound cytochrome b558, is required for activation of the latent NADPH oxidase necessary for superoxide production. Defects in NCF1 are the cause of autosomal cytochrome-b-positive chronic granulomatous disease type 1 (CGD). NCF1 is a cytosolic subunit of the multi-protein complex known as NADPH oxidase found in neutrophils.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Additional NCF1 Products

Array NBP2-98530AF488

Research Areas for NCF1 Antibody (NBP2-98530AF488)

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Blogs on NCF1.

Identifying tumoral and stromal transcriptomes that underlie tumor plasticity and stromal neuroinflammatory response in brain metastasis
By Jamshed Arslan, Pharm. D., PhD. Cancers in the brain often come from tumors elsewhere in the body. Several adaptive mechanisms influence brain metastasis, such as blood brain barrier leakage that can be induced by ...  Read full blog post.

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Bioinformatics

Gene Symbol NCF1