Species: Hu, Mu, Rt, Po, Ba, Bv
Applications: WB, ELISA, Flow, ICC/IF, IHC, IP
Host: Goat Polyclonal
Species: Hu, Mu, Rt, Po, Bv, Ca
Applications: WB, ELISA, ICC/IF
Host: Goat Polyclonal
Species: Hu
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
NCF1, along with NCF2 and a membrane bound cytochrome b558, is required for activation of the latent NADPH oxidase necessary for superoxide production. Defects in NCF1 are the cause of autosomal cytochrome-b-positive chronic granulomatous disease type 1 (CGD). NCF1 is a cytosolic subunit of the multi-protein complex known as NADPH oxidase found in neutrophils.
Bioinformatics
Uniprot |
Human Human Human Human |
Product By Gene ID |
653361 |
Alternate Names |
- 47 kDa neutrophil oxidase factor
- FLJ79451
- NADPH oxidase organizer 2
- NCF-1
- NCF1A
- neutrophil cytosol factor 1,47 kDa autosomal chronic granulomatous disease protein
- neutrophil cytosolic factor 1 (47kD, chronic granulomatous disease, autosomal1)
- neutrophil cytosolic factor 1
- neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1)
- Neutrophil NADPH oxidase factor 1
- Nox organizer 2
- NOXO2NCF-47K
- Nox-organizing protein 2
- p47phox
- SH3 and PX domain-containing protein 1A
- SH3PXD1Ap47-phox
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