KLH-conjugated, synthetic peptide containing the sequence.RS[pT]GV., in which [pT] corresponds to phosphorylated threonine at amino acid residue 850 of chicken myosin phosphatase target subunit 1 (MYPT1). Corresponds to Thr853 in human MYPT1.
Modification
p Thr853
Specificity
MYPT1 phosphorylated on Thr850 doublet at 130kDa weight may be detected.
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
PPP1R12A
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
(0.1M Tris-glycine, pH 7.4, 0.15M NaCl, and 30% glycerol
Preservative
No Preservative
Purity
Protein A or G purified
Notes
Relevant Entrez Gene Numbers: NM_002480
Alternate Names for Myosin Phosphatase [p Thr853] Antibody (SA19)
MBSmyosin phosphatase, target subunit 1
MGC133042
Myosin phosphatase target subunit 1
Myosin phosphatase-targeting subunit 1
MYPT1protein phosphatase 1 regulatory subunit 12A
protein phosphatase 1, regulatory (inhibitor) subunit 12A
Protein phosphatase myosin-binding subunit
Background
The major protein phosphatase-1 (PP1) is composed of 3 subunits with apparent molecular mass of 110-130, 37 & 20 kDa. The 110-130 kDa component act as a regulatory subunit known as myosine binding (MBS) or myosine phosphatae targeting subunit (MYPT). The N-terminal portion of MYPT binds to both PP1c-delta and phosphorylated myosin, thereby increasing myosin phosphatase activity. Two isoform of MYPT have been identified (MYPT1 & MYPT2) and share 61% sequence identity. While MYPT1 is widely distributed in human tissues, MYPT2 is mostly detected in brain and heart.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Reviews for Myosin Phosphatase Antibody (NBP2-29680) (0)
There are no reviews for Myosin Phosphatase Antibody (NBP2-29680).
By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
Product General Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.
=
÷
Review this Product
Be the first to review our Myosin Phosphatase [p Thr853] Antibody (SA19) and receive a gift card or discount.