Mouse IL-3 DuoSet ELISA, 15 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Interleukin-3 (IL-3) is a secreted cytokine that stimulates the proliferation and differentiation of pluripotent hematopoietic stem cells and various lineage-committed progenitors. It also regulates the activation of mature mast cells, basophils, eosinophils, and macrophages. It is produced by activated T cells, thymic epithelial cells, activated mast cells, keratinocytes, neurons, and astrocytes. IL-3 signals through a receptor complex that contains IL-3 R alpha/CD123 and the common beta chain which is also a component of the receptors for IL-5 and GM-CSF. Receptors for IL-3 are present on bone marrow progenitors, macrophages, mast cells, eosinophils, megakaryocytes, basophils, and various myeloid leukemic cells. Human IL-3 does not show activity on mouse cells.

We have publications tested in 1 confirmed species: Mouse.

Showing Publications 1 - 3 of 3.

Publications using DY403	Applications	Species
M Reitz, ML Brunn, D Voehringer, M Breloer Basophils are dispensable for the establishment of protective adaptive immunity against primary and challenge infection with the intestinal helminth parasite Strongyloides ratti PLoS Negl Trop Dis, 2018-11-29;12(11):e0006992. 2018-11-29 [PMID: 30496188] (Mouse)		Mouse
Blankenhaus B, Reitz M, Brenz Y, Eschbach M, Hartmann W, Haben I, Sparwasser T, Huehn J, Kuhl A, Feyerabend T, Rodewald H, Breloer M Foxp3(+) regulatory T cells delay expulsion of intestinal nematodes by suppression of IL-9-driven mast cell activation in BALB/c but not in C57BL/6 mice. PLoS Pathog, 2014-02-06;10(2):e1003913. 2014-02-06 [PMID: 24516385] (Mouse)		Mouse
Munitz A, Bachelet I, Eliashar R, Khodoun M, Finkelman FD, Rothenberg ME, Levi-Schaffer F CD48 is an allergen and IL-3-induced activation molecule on eosinophils. J. Immunol., 2006-07-01;177(1):77-83. 2006-07-01 [PMID: 16785501] (Mouse)		Mouse

Array DY403

• IL-3 Antibodies
• IL-3 Antibody Pair
• IL-3 ELISA Kits
• IL-3 Lysate
• IL-3 Proteins
• IL-3 ELISAs
• IL-3 Proteins and Enzymes