Mouse CXCL12/SDF-1 DuoSet ELISA, 15 Plate

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CXCL12/Stromal Cell-derived Factor 1 (SDF-1) is a member of the CXC chemokine ligand superfamily. Six alternatively spliced CXCL12/SDF-1 isoforms have been identified including, CXCL12/SDF-1 alpha, CXCL12/SDF-1 beta, and CXCL12/SDF-1 gamma. CXCL12/SDF-1 alpha is 89 amino acids (aa) in length with a predicted molecular weight of 10 kDa, CXCL12/SDF-1 beta is 93 aa in length with a predicted molecular weight of 10.6 kDa, and CXCL12/SDF-1 gamma is 119 aa in length with a predicted molecular weight of 13.7 kDa. The mouse CXCL12/SDF-1 orthologs share 99% aa sequence identity with the human protein. The alpha and beta isoforms are ubiquitously expressed while the gamma isoform is primarily expressed in the heart. CXCL12/SDF-1 isoforms are chemotactic for T lymphocytes and monocytes. It is cardio protective and has also been shown to hinder CXCR4-mediated HIV infection of T cells.

We have publications tested in 2 confirmed species: Human, Mouse.

Showing Publications 1 - 10 of 26. Show All 26 Publications. Collapse Publications.

Publications using DY460	Applications	Species
Morgaenko, K;Arneja, A;Ball, AG;Putelo, AM;Munson, JM;Rutkowski, MR;Pompano, RR; Ex vivo model of breast cancer cell invasion in live lymph node tissue bioRxiv : the preprint server for biology 2024-07-22 [PMID: 39091774] (Mouse)		Mouse
Colella, P;Sayana, R;Suarez-Nieto, MV;Sarno, J;Nyame, K;Xiong, J;Pimentel Vera, LN;Arozqueta Basurto, J;Corbo, M;Limaye, A;Davis, KL;Abu-Remaileh, M;Gomez-Ospina, N; CNS-wide repopulation by hematopoietic-derived microglia-like cells corrects progranulin deficiency in mice Nature communications 2024-07-05 [PMID: 38969669] (Mouse)		Mouse
L Spagnuolo, V Puddinu, N Boss, T Spinetti, A Oberson, J Widmer, I Mottas, C Hotz, ME Bianchi, M Uguccioni, C Bourquin HMGB1 promotes CXCL12-dependent egress of murine B cells from Peyer's patches in homeostasis European Journal of Immunology, 2021-06-16;0(0):. 2021-06-16 [PMID: 34060652] (Mouse)		Mouse
A Di Pardo, E Ciaglia, M Cattaneo, A Maciag, F Montella, V Lopardo, A Ferrario, F Villa, M Madonna, E Amico, A Carrizzo, A Damato, G Pepe, F Marracino, A Auricchio, C Vecchione, V Maglione, AA Puca The longevity-associated variant of BPIFB4 improves a CXCR4-mediated striatum-microglia crosstalk preventing disease progression in a mouse model of Huntington's disease Cell Death Dis, 2020-07-18;11(7):546. 2020-07-18 [PMID: 32683420] (Mouse)		Mouse
LE Hand, KJ Gray, SH Dickson, DA Simpkins, DW Ray, JE Konkel, MR Hepworth, JE Gibbs Regulatory T cells confer a circadian signature on inflammatory arthritis Nat Commun, 2020-04-03;11(1):1658. 2020-04-03 [PMID: 32245954] (Mouse)		Mouse
M Xu, C Ge, Y Qin, D Lou, Q Li, J Feng, Y Wu, L Hu, B Wang, J Tan Functional loss of inactive rhomboid-like protein�2 mitigates obesity by suppressing pro-inflammatory macrophage activation-triggered adipose inflammation Mol Metab, 2020-01-22;34(0):112-123. 2020-01-22 [PMID: 32180551] (Mouse)		Mouse
BJ Meijer, FP Giugliano, B Baan, JHM van der Me, S Meisner, M van Roest, PJ Koelink, RJ de Boer, N Jones, W Breitwiese, NN van der We, ME Wildenberg, GR van den Br, J Heijmans, V Muncan ATF2 and ATF7 Are Critical Mediators of Intestinal Epithelial Repair Cell Mol Gastroenterol Hepatol, 2020-01-17;0(0):. 2020-01-17 [PMID: 31958521] (Mouse)		Mouse
LN Zamproni, D Teixeira, A Arnaut All, I Longo Maug, A des Rieux, MA Porcionatt Decreased viability and neurite length in neural cells treated with chitosan-dextran sulfate nanocomplexes Neurotoxicology, 2019-10-09;76(0):33-43. 2019-10-09 [PMID: 31605718] (Mouse)		Mouse
FH Brennan, T Jogia, ER Gillespie, LV Blomster, XX Li, B Nowlan, GM Williams, E Jacobson, GW Osborne, FA Meunier, SM Taylor, KE Campbell, KP MacDonald, JP Levesque, TM Woodruff, MJ Ruitenberg Complement receptor C3aR1 controls neutrophil mobilization following spinal cord injury through physiological antagonism of CXCR2 JCI Insight, 2019-05-02;4(9):. 2019-05-02 [PMID: 31045582] (Mouse)		Mouse
S Avraham, B Korin, S Aviram, D Shechter, Y Shaked, A Aronheim ATF3 and JDP2 deficiency in cancer associated fibroblasts promotes tumor growth via SDF-1 transcription Oncogene, 2019-01-22;0(0):. 2019-01-22 [PMID: 30670778] (Mouse)		Mouse
B Wang, Y Guo, X Chen, C Zeng, Q Hu, W Yin, W Li, H Xie, B Zhang, X Huang, F Yu Nanoparticle-modified chitosan-agarose-gelatin scaffold for sustained release of SDF-1 and BMP-2 Int J Nanomedicine, 2018-11-12;13(0):7395-7408. 2018-11-12 [PMID: 30519022] (Human)		Human
K Bröker, J Figge, AF Magnusen, RA Manz, J Köhl, CM Karsten A Novel Role for C5a in B-1 Cell Homeostasis Front Immunol, 2018-02-19;9(0):258. 2018-02-19 [PMID: 29520270] (Mouse)		Mouse
W Alturaiki, AJ McFarlane, K Rose, R Corkhill, PS McNamara, J Schwarze, BF Flanagan Expression of the B cell differentiation factor BAFF and chemokine CXCL13 in a murine model of Respiratory Syncytial Virus infection Cytokine, 2018-02-01;0(0):. 2018-02-01 [PMID: 29396045] (Human)		Human
BF Westendorp, NVJA Büller, ON Karpus, WA van Dop, J Koster, R Versteeg, PJ Koelink, CY Snel, S Meisner, JJTH Roelofs, A Uhmann, E Ver Loren, J Heijmans, H Hahn, V Muncan, ME Wildenberg, GR van den Br Indian Hedgehog Suppresses a Stromal Cell-Driven Intestinal Immune Response Cell Mol Gastroenterol Hepatol, 2017-09-05;5(1):67-82.e1. 2017-09-05 [PMID: 29276753] (Mouse)		Mouse
P Marona, J Górka, Z Mazurek, W Wilk, J Rys, M Majka, J Jura, K Miekus MCPIP1 downregulation in clear cell renal cell carcinoma promotes vascularization and metastatic progression Cancer Res., 2017-07-17;0(0):. 2017-07-17 [PMID: 28716897] (Mouse)		Mouse
B Isaacson, T Hadad, A Glasner, C Gur, Z Granot, G Bachrach, O Mandelboim Stromal Cell-Derived Factor 1 Mediates Immune Cell Attraction upon Urinary Tract Infection Cell Rep, 2017-07-05;20(1):40-47. 2017-07-05 [PMID: 28683322] (Mouse)		Mouse
M Losada-Bar, A Umaña-Pére, S Cuervo-Esc, LR Berbert, R Porrozzi, FN Morgado, DA Mendes-da-, W Savino, M Sánchez-Gó, P Cuervo Protein malnutrition promotes dysregulation of molecules involved in T cell migration in the thymus of mice infected with Leishmania infantum Sci Rep, 2017-04-11;7(0):45991. 2017-04-11 [PMID: 28397794] (Mouse)		Mouse
SDF-1?-induced dual pairs of E-selectin/ligand mediate endothelial progenitor cell homing to critical ischemia Sci Rep, 2016-10-07;6(0):34416. 2016-10-07 [PMID: 27713493] (Human)		Human
The time-of-day of myocardial infarction onset affects healing through oscillations in cardiac neutrophil recruitment EMBO Mol Med, 2016-08-01;0(0):. 2016-08-01 [PMID: 27226028] (Mouse)		Mouse
Barreira da Silva R, Laird M, Yatim N, Fiette L, Ingersoll M, Albert M Dipeptidylpeptidase 4 inhibition enhances lymphocyte trafficking, improving both naturally occurring tumor immunity and immunotherapy. Nat Immunol, 2015-06-15;16(8):850-8. 2015-06-15 [PMID: 26075911] (Mouse)		Mouse
Projahn D, Simsekyilmaz S, Singh S, Kanzler I, Kramp B, Langer M, Burlacu A, Bernhagen J, Klee D, Zernecke A, Hackeng T, Groll J, Weber C, Liehn E, Koenen R Controlled intramyocardial release of engineered chemokines by biodegradable hydrogels as a treatment approach of myocardial infarction. J Cell Mol Med, 2014-02-06;18(5):790-800. 2014-02-06 [PMID: 24512349] (Mouse)		Mouse
Przybyla B, Shafirstein G, Vishal S, Dennis R, Griffin R Molecular changes in bone marrow, tumor and serum after conductive ablation of murine 4T1 breast carcinoma. Int J Oncol, 2013-11-21;44(2):600-8. 2013-11-21 [PMID: 24270800] (Mouse)		Mouse
Ponzetta A, Sciume G, Benigni G, Antonangeli F, Morrone S, Santoni A, Bernardini G CX3CR1 regulates the maintenance of KLRG1+ NK cells into the bone marrow by promoting their entry into circulation. J Immunol, 2013-11-01;191(11):5684-94. 2013-11-01 [PMID: 24184559] (Mouse)		Mouse
Schiraldi M, Raucci A, Munoz LM, Livoti E, Celona B, Venereau E, Apuzzo T, De Marchis F, Pedotti M, Bachi A, Thelen M, Varani L, Mellado M, Proudfoot A, Bianchi ME, Uguccioni M HMGB1 promotes recruitment of inflammatory cells to damaged tissues by forming a complex with CXCL12 and signaling via CXCR4. J. Exp. Med., 2012-02-27;209(3):551-63. 2012-02-27 [PMID: 22370717] (Mouse)		Mouse
Hughes DJ, Kipar A, Leeming GH, Bennett E, Howarth D, Cummerson JA, Papoula-Pereira R, Flanagan BF, Sample JT, Stewart JP Chemokine binding protein M3 of murine gammaherpesvirus 68 modulates the host response to infection in a natural host. PLoS Pathog., 2011-03-17;7(3):e1001321. 2011-03-17 [PMID: 21445235] (Mouse)		Mouse
Jung Y, Wang J, Schneider A, Sun YX, Koh-Paige AJ, Osman NI, McCauley LK, Taichman RS Regulation of SDF-1 (CXCL12) production by osteoblasts; a possible mechanism for stem cell homing. Bone, 2005-12-05;38(4):497-508. 2005-12-05 [PMID: 16337237] (Mouse)		Mouse
Show All 26 Publications. Collapse Publications.

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• CXCL12/SDF-1 Antibodies
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