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MNK2 Antibody - b Isoform

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Western Blot: MNK2 Antibody - b Isoform [NBP2-60786] - Mnk2 Antibody - b Isoform [NBP2-60786] - Western blot of HeLa lysate showing specific immunolabeling of the ~47 kDa Mnk2b isoform in the first lane (-). Specificity ...read more

Product Details

Summary
Reactivity Hu, PmSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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MNK2 Antibody - b Isoform Summary

Immunogen
Synthetic peptide from the C-terminal region, specific to the human Mnk2b isoform. Accession # Q9HBH9
Specificity
Specific for endogenous levels of the ~47 kDa MNK2 protein. Immunolabeling is blocked by preadsorption with the MNK2 peptide used as antigen, but not by Mnk2a peptide.
Predicted Species
Primate (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MKNK2
Purity
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
Theoretical MW
47 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
10 mM HEPES (pH 7.5), 0.15 M NaCl, 0.1 mg/mL BSA, 50% Glycerol
Preservative
No Preservative
Purity
Antigen Affinity-purified

Alternate Names for MNK2 Antibody - b Isoform

  • EC 2.7.11
  • EC 2.7.11.1
  • G protein-coupled receptor kinase 7
  • GPRK7Putative map kinase interacting kinase
  • MAP kinase interacting serine/threonine kinase 2
  • MAP kinase signal-integrating kinase 2
  • MKNK2
  • MNK2
  • MNK2MAP kinase-interacting serine/threonine-protein kinase 2

Background

MNK2 may play a role in the response to environmental stress and cytokines. Appears to regulate transcription byphosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol MKNK2