MMP-7 Antibody [Biotin]

Matrix Metalloproteinases (MMPs) belong to a family of proteases that are essential for the breakdown of extracellular matrix (ECM). They are important in tumor cell growth, invasion, and metastasis, as well as angiogenesis, wound healing, and apoptosis. Most MMPs contain common domain structures that include a signal sequence, a propeptide, a catalytic domain, and a hemopexin like (Hpx) domain. Matrix metalloproteinase-7 (MMP7), also known as Matrilysin, belongs to the peptidase M10A family, and is responsible for hydrolyzing proteoglycans and ECM glycoproteins. MMP7 will activate procollagenase while degrading gelatin types I, III, IV, and V, and casein. In addition, MMP7 is expressed in normal and cancer cells, specifically glandular epithelial cells and pancreatic carcinoma. Research suggests that MMP7 may play an important role in the early stages of tumor progression.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Array NBP1-99123B

• MMP-7 Antibodies
• MMP-7 ELISA Kits
• MMP-7 Lysate
• MMP-7 Protein
• MMP-7 ELISAs
• MMP-7 Proteins and Enzymes