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MMP-24/MT5-MMP Antibody (143908) [DyLight 488]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, Flow, CyTOF-ready
Clone
143908
Clonality
Monoclonal
Host
Rat
Conjugate
DyLight 488

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
IC924U-100UG
Alexa Fluor 405
IC924V-100UG
Alexa Fluor 532
FAB924X
Alexa Fluor 594
IC924T-100UG
Alexa Fluor 647
IC924R-100UG
Alexa Fluor 700
IC924N-100UG
Alexa Fluor 750
IC924S-100UG
Allophycocyanin/Cy7
FAB924APCCY7
Biotin
FAB924B
DyLight 350
FAB924D
DyLight 405
FAB924E
DyLight 550
FAB924L
DyLight 594
FAB924M
DyLight 650
FAB924W
DyLight 680
FAB924Y
DyLight 755
FAB924Z
FITC
FAB924F
HRP
FAB924H
Janelia Fluor 525
FAB924JF525
Janelia Fluor 549
FAB924I
Janelia Fluor 585
FAB924JF585
Janelia Fluor 635
FAB924JF635
Janelia Fluor 646
FAB924J
Janelia Fluor 669
FAB924JF669
PE/Atto594
FAB924PEATT594
PE/Cy5.5
FAB924PECY55
PE/Cy7
FAB924PECY7
PerCP
FAB924C
Unconjugated
MAB924
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB924
Carrier Free
MAB924
Carrier Free
MAB924-SP
Carrier Free
IC924V-100UG
Carrier Free
IC924N-100UG
Carrier Free
IC924U-100UG
Carrier Free
IC924T-100UG
Carrier Free
IC924S-100UG
Carrier Free
IC924R-100UG
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MMP-24/MT5-MMP Antibody (143908) [DyLight 488] Summary

Immunogen
E. coli-derived recombinant mouse MMP‑24/MT5-MMP
Arg125-Gln296
Accession # Q9R0S2
Specificity
Detects mouse MMP‑24/MT5-MMP in direct ELISAs and detects human and mouse MMP‑24/MT5-MMP in Western blots. In Western blots, less than 5% cross-reactivity with recombinant mouse (rm) MMP-3, rmMMP-9, and the catalytic domains of recombinant human MMP‑14, 15, and 16 is observed.
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
MMP24
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for MMP-24/MT5-MMP Antibody (143908) [DyLight 488]

  • EC 3.4.24
  • EC 3.4.24.-
  • EC 3.4.24.80
  • matrix metallopeptidase 24 (membrane-inserted)
  • matrix metalloproteinase 24 (membrane-inserted)
  • matrix metalloproteinase-24
  • membrane-type 5 matrix metalloproteinase
  • Membrane-type matrix metalloproteinase 5
  • Membrane-type-5 matrix metalloproteinase
  • MMP24
  • MMP-24
  • MT5MMP
  • MT5-MMP
  • MT5-MMPMMP25
  • MT-MMP 5
  • MTMMP5
  • MT-MMP5

Background

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 by cleavage. The gene has previously been referred to as MMP25 but has been renamed MMP24. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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MMP-24/MT5-MMP
Antibody (143908) [Dy ...
FAB924K
MMP-24/MT5-MMP Antibody (143908) [DyLight 488]
Species: Hu, Mu
Applications: WB, Flow, CyTOF-ready

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol MMP24