MMP-11 Antibody (SN74-08)

The matrix metalloproteinases are a tightly regulated family of enzymes that degrade extracellular matrix and basement membrane components. Recent evidence suggests that these proteases and their specific inhibitors play important roles in normal developmental processes and in pathological conditions (1). MMP-11 (stromelysin-3), a new member of the matrix metalloproteinase family, is expressed in tissues undergoing the active remodeling associated with embryonic development, wound healing and tumor invasion. But like all other members of the matrix metalloproteinase gene family, stromelysin-3 is synthesized as an inactive precursor that must be processed to its mature form in order to express enzymic activity (2). MMP-11, like an inflammatory mediator, may exert a chemotactic influence on macrophages which aggregate in the mesangium; MMP-11 is not likely to have a parallel mitogenic or antifibrotic effect in diseased glomeruli (3).

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 2 applications: IHC-P, WB.

Showing Publications 1 - 6 of 6.

Publications using NBP2-67670	Applications	Species
Jeong Won Lee, Hyein Ahn, Ik Dong Yoo, Sun-pyo Hong, Moo-Jun Baek, Dong Hyun Kang, Sang Mi Lee Relationship of FDG PET/CT imaging features with tumor immune microenvironment and prognosis in colorectal cancer: a retrospective study Cancer Imaging 2024-04-16 [PMID: 38627864]
Ahn H, Song GJ, Jang SH et al. Predicting the Recurrence of Gastric Cancer Using the Textural Features of Perigastric Adipose Tissue on [18F]FDG PET/CT International journal of molecular sciences 2022-10-09 [PMID: 36233285] (IHC-P, Human)	IHC-P	Human
Ahn H, Song GJ, Jang SH et al. Relationship of FDG PET/CT Textural Features with the Tumor Microenvironment and Recurrence Risks in Patients with Advanced Gastric Cancers Cancers 2022-08-15 [PMID: 36010928] (IHC-P, Human)	IHC-P	Human
Kim DJ, Iwasaki A, Chien AL, Kang S UVB-mediated DNA damage induces matrix metalloproteinases to promote photoaging in an AhR- and SP1-dependent manner JCI insight 2022-03-22 [PMID: 35316219]
Ahn H, Won Lee J, Jang SH Et al. Prognostic significance of imaging features of peritumoral adipose tissue in FDG PET/CT of patients with colorectal cancer European journal of radiology 2021-11-17 [PMID: 34801879] (IHC-P, Human)	IHC-P	Human
Wang Y, Hu S, Yao G, Sun Y Identification of HOXA10 target genes in human endometrial stromal cells by RNA-seq analysis Acta biochimica et biophysica Sinica 2021-01-19 [PMID: 33462609] (WB, Mouse)	WB	Mouse

Array NBP2-67670

• MMP-11 Antibodies
• MMP-11 ELISA Kits
• MMP-11 Protein