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MICB Antibody (236511) [Janelia Fluor® 585]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, CyTOF-ready, ELISA, ELISA(Cap), ELISA(Det), KO
Clone
236511
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 585

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB1599U-100UG
Alexa Fluor 405
FAB1599V-100UG
Alexa Fluor 488
FAB1599G-025
Alexa Fluor 488
FAB1599G-100
Alexa Fluor 532
FAB1599X
Alexa Fluor 594
FAB1599T-100UG
Alexa Fluor 647
FAB1599R-100UG
Alexa Fluor 700
FAB1599N-025
Alexa Fluor 700
FAB1599N-100
Alexa Fluor 750
FAB1599S-100UG
Allophycocyanin
FAB1599A-025
Allophycocyanin
FAB1599A-100
Allophycocyanin/Cy7
FAB1599APCCY7
Biotin
FAB1599B
CoraFluor 1
FAB1599CL1
DyLight 350
FAB1599D
DyLight 405
FAB1599E
DyLight 488
FAB1599K
DyLight 550
FAB1599L
DyLight 594
FAB1599M
DyLight 650
FAB1599W
DyLight 680
FAB1599Y
DyLight 755
FAB1599Z
FITC
FAB1599F
HRP
FAB1599H
Janelia Fluor 525
FAB1599JF525
Janelia Fluor 549
FAB1599I
Janelia Fluor 635
FAB1599JF635
Janelia Fluor 646
FAB1599J
Janelia Fluor 669
FAB1599JF669
PE/Atto594
FAB1599PEATT594
PE/Cy5.5
FAB1599PECY55
PE/Cy7
FAB1599PECY7
Phycoerythrin
FAB1599P-100
Phycoerythrin
FAB1599P-025
Unconjugated
MAB1599-100
mFluor Violet 450 SE
FAB1599MFV450
mFluor Violet 500 SE
FAB1599MFV500
mFluor Violet 610 SE
FAB1599MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB1599-100
Carrier Free
MAB1599-SP
Carrier Free
FAB1599S-100UG
Carrier Free
FAB1599T-100UG
Carrier Free
FAB1599U-100UG
Carrier Free
FAB1599V-100UG
Carrier Free
MAB1599-100
Carrier Free
MAB1599-500
Carrier Free
FAB1599N-100
Carrier Free
FAB1599P-025
Carrier Free
FAB1599N-025
Carrier Free
FAB1599G-100
Carrier Free
FAB1599G-025
Carrier Free
FAB1599A-100
Carrier Free
FAB1599A-025
Carrier Free
FAB1599P-100
Carrier Free
FAB1599R-100UG
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MICB Antibody (236511) [Janelia Fluor® 585] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human MICB
Ala23-Gly298
Accession # CAI18747
Specificity
Detects human MICB in direct ELISAs and Western blots. Does not cross-react with recombinant human MICA.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
MICB
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • ELISA Capture (Matched Antibody Pair)
  • ELISA Detection (Matched Antibody Pair)
  • ELISA Standard (Matched Pair)
  • Flow Cytometry
  • Knockout Validated
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for MICB Antibody (236511) [Janelia Fluor® 585]

  • MHC class I chain-related protein B
  • MHC class I mic-B antigen
  • MHC class I polypeptide-related sequence B
  • MICB
  • MIC-B
  • PERB11.2MHC class I-like molecule PERB11.2-IMX
  • stress inducible class I homolog

Background

MICB encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Blogs on MICB.

Check out the latest blog posts on MICB.
Harnessing Natural Killer Cell Activity for Anti-Tumor Immunotherapy
By Victoria Osinski, PhDWhat’s “Natural” About Natural Killer (NK) Cells?For immunologists, the term cytotoxicity often conjures up images of an army of antigen specific CD8+ T cells deploying to ...  Read full blog post.
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Bioinformatics

Gene Symbol MICB