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mGluR2 Antibody (455310) [Janelia Fluor® 525]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, CyTOF-ready, Flow
Clone
455310
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 525

Order Details

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mGluR2 Antibody (455310) [Janelia Fluor® 525] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human mGluR2
Glu19-Ser498
Accession # Q14416
Specificity
Detects human mGluR2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross‑reactivity with the N-terminal regions of recombinant human mGluR1, -3, -4, -5, -7, or -8 is observed.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
GRM2
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Intracellular Staining by Flow Cytometry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for mGluR2 Antibody (455310) [Janelia Fluor® 525]

  • GLUR2
  • glutamate metabotropic receptor 2
  • glutamate receptor, metabotropic 2
  • GPRC1B
  • GPRC1Bmetabotropic glutamate receptor 2
  • GRM2
  • mGlu2
  • mGluR2
  • MGLUR2glutamate receptor homolog
  • mGluR7

Background

The Metabotropic Glutamate Receptor GRM2 binds L-glutamate and has been linked to the inhibition of the cyclic AMP signaling cascade. GRM2 is involved in mediating the suppression of neurotransmission and in synaptogenesis and synaptic stabilization. Glutamatergic neurotransmission plays a role in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. GRM2 has been reported in various regions of the human and animal brain, as well as in rat eye and spinal cord. ESTs have been isolated from brain and testis libraries. Caution: GLUR2 refers to Ionotropic Glutamate Receptor 2, not to Metabotropic Glutamate Receptor 2 (mGLUR2).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol GRM2