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Methionine Sulfoxide Reductase A Antibody

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Western Blot: Methionine Sulfoxide Reductase A Antibody [NBP1-87456] - Analysis in human cell line WM-115.
Immunocytochemistry/ Immunofluorescence: Methionine Sulfoxide Reductase A Antibody [NBP1-87456] - Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm, cytosol & actin filaments.
Immunohistochemistry-Paraffin-Methionine Sulfoxide Reductase A Antibody-NBP1-87456- Staining of human kidney shows strong nuclear and cytoplasmic positivity in cells in tubules.
Immunohistochemistry-Paraffin-Methionine Sulfoxide Reductase A Antibody-NBP1-87456-Staining of human colon shows strong nuclear and cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin-Methionine Sulfoxide Reductase A Antibody-NBP1-87456-Staining of human testis shows moderate nuclear and cytoplasmic positivity in cells in seminiferous ducts.
Immunohistochemistry-Paraffin-Methionine Sulfoxide Reductase A Antibody-NBP1-87456-Staining of human skeletal muscle shows no positivity in myocytes as expected.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Methionine Sulfoxide Reductase A Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: ASNIVSPQEALPGRKEQTPVAAKHHVNGNRTVEPFPEGTQMAVFGMGCFWGAERKFWVLKGVYSTQVG
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MSRA
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:500 - 1:1000
  • Immunohistochemistry-Paraffin 1:500 - 1:1000
  • Western Blot 0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
Methionine Sulfoxide Reductase A Protein (NBP1-87456PEP)
Publications
Read Publication using
NBP1-87456 in the following applications:

  • WB
    1 publication

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (85%), Rat (84%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Methionine Sulfoxide Reductase A Antibody

  • cytosolic methionine-S-sulfoxide reductase
  • EC 1.8.4.11
  • methionine sulfoxide reductase A
  • peptide met (O) reductase
  • Peptide Met(O) reductase
  • peptide methionine sulfoxide reductase
  • Peptide-methionine (S)-S-oxide reductase
  • PMSR
  • Protein-methionine-S-oxide reductase

Background

This protein is ubiquitous and highly conserved. It carries out the enzymatic reduction of methionine sulfoxide to methionine. Human and animal studies have shown the highest levels of expression in kidney and nervous tissue. Its proposed function is the repair of oxidative damage to proteins to restore biological activity. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Methionine Sulfoxide Reductase A Antibody (NBP1-87456)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: WB.


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(1)
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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Bioinformatics

Gene Symbol MSRA