Melatonin Receptor 1B Antibody [DyLight 550] Summary
Immunogen |
A synthetic peptide made to an internal region of the human Melatonin Receptor 1B protein (within residues 200-300) [Swiss-Prot P49286]. |
Localization |
Cell membrane; Multi-pass membrane protein. |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Rabbit |
Gene |
MTNR1B |
Purity |
Immunogen affinity purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunohistochemistry 1:100
- Immunohistochemistry-Frozen
- Immunohistochemistry-Paraffin 1:100
- Knockdown Validated
- Western Blot 1:1000
|
Application Notes |
Optimal dilution of this antibody should be experimentally determined. |
Reactivity Notes
Chicken reactivity reported in scientific literature (PMID:32758663).
Packaging, Storage & Formulations
Storage |
Store at 4C in the dark. |
Buffer |
50mM Sodium Borate |
Preservative |
0.05% Sodium Azide |
Purity |
Immunogen affinity purified |
Notes
DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
Alternate Names for Melatonin Receptor 1B Antibody [DyLight 550]
Background
Melatonin receptor type 1B (MTNR1B) is a member of the G-protein coupled receptor 1 family. This family is responsible for translating external chemical signals across the cell membrane. MTNR1B is one of two high affinity receptors for melatonin, a hormone secreted by the pineal gland. Pertussis toxin sensitive G proteins, that inhibit adenylate cyclase activity, control the MTNR1B receptor. MTNR1B is expressed in the retina, and to a lesser extent the brain and hippocampus. MTNR1B is thought to regulate reproduction, the circadian cycle, and neurological melatonin levels; as well as participate in light dependent function in the retina. Post translational modifications that may affect MTNR1B are disulfide bonds and glycosylation.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
Customers Who Viewed This Item Also Viewed...
Species: Rt
Applications: PEP-ELISA, WB
Species: Hu
Applications: ELISA, AP, PA, WB
Species: Hu
Applications: WB
Species: Hu
Applications: ELISA, AP, PA, PAGE, WB
Species: Hu
Applications: ELISA, AP, PA, PAGE, WB
Species: Hu
Applications: WB
Species: Hu
Applications: ELISA, AP, PA, WB
Species: Hu
Applications: ELISA, AP, PA, WB
Species: Hu
Applications: ELISA, AP, PA, PAGE, WB
Species: Hu
Applications: ELISA, IHC, IHC-P, S-ELISA, WB
Species: Hu, Mu
Applications: ICC/IF, IHC, IHC-P
Species: Bv, Hu, Mu
Applications: CyTOF-ready, ICC, IHC, ICFlow
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P, WB
Species: Hu, Mu
Applications: Flow-IC, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, WB
Species: Hu
Applications: CyTOF-ready, ELISA, Flow, ICC/IF, IHC, IHC-P, PA, WB
Species: Hu
Applications: BA
Species: Hu, Mu
Applications: ELISA, ICC/IF, IHC, WB
Species: Hu, Mu, Rt
Applications: ICC/IF, WB
Publications for Melatonin Receptor 1B Antibody (NLS932R) (0)
There are no publications for Melatonin Receptor 1B Antibody (NLS932R).
By submitting your publication information earn gift cards and discounts for future purchases.
Reviews for Melatonin Receptor 1B Antibody (NLS932R) (0)
There are no reviews for Melatonin Receptor 1B Antibody (NLS932R).
By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
- Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
- Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
Product General Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
Video Protocols
FAQs for Melatonin Receptor 1B Antibody (NLS932R). (Showing 1 - 1 of 1 FAQ).
-
I saw that you have the antibodies for the both receptors of melatonin but not listed with FACS application. I need more information about what is better for my assay.
- At this time, none of our melatonin receptor antibodies have been tested and validated in Flow. Should you choose to purchase and test one of them, you would qualify for the Innovator's Rewards program. You should take a look at each individual antibody, the clonality, conjugates, immunogen region and all relevant data in order to decide which product would be most suitable for your needs.
Secondary Antibodies
| |
Isotype Controls
|
Additional Melatonin Receptor 1B Products
Research Areas for Melatonin Receptor 1B Antibody (NLS932R)
Find related products by research area.
|
Blogs on Melatonin Receptor 1B