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MBD2 Antibody

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Western Blot: MBD2 Antibody [NBP3-18692] - Figure 1. Western blot analysis using the antibody directed against MBD2 Whole cell extracts (40 ug) from HeLa cells, transfected with a TY1-tagged MBD2 (lane 2) or an ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.2 mg/ml

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MBD2 Antibody Summary

Immunogen
Polyclonal antibody raised in rabbit against mouse MBD2 (methyl-CpG binding domain protein 2), using a recombinant protein.
Clonality
Polyclonal
Host
Rabbit
Gene
MBD2
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:1000

Packaging, Storage & Formulations

Storage
Store at -20C short term. Aliquot and store at -80C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.05% Sodium Azide and 0.05% ProClin 300
Concentration
1.2 mg/ml
Purity
Protein G purified

Alternate Names for MBD2 Antibody

  • Demethylase
  • DKFZp586O0821
  • DMTase
  • MBD2
  • methyl-CpG binding domain protein 2
  • methyl-CpG-binding domain protein 2
  • Methyl-CpG-binding protein MBD2
  • NY-CO-41

Background

DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. The protein encoded by this gene may function as a mediator of the biological consequences of the methylation signal. It is also reported that the this protein functions as a demethylase to activate transcription, as DNA methylation causes gene silencing. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Array NBP3-18692

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Bioinformatics

Gene Symbol MBD2
Uniprot