MAP3K12 Antibody [FITC]

The protein encoded by the MAP3K12 gene is a member of serine/threonine protein kinase family. This kinase contains a leucine-zipper domain, and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation. (provided by RefSeq)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Showing Publications 1 - 6 of 6.

Publications using NBP1-62734	Applications	Species
[PMID: 15749080]. Expression of MUK/DLK/ZPK, an activator of the JNK pathway, in the nervous systems of the developing mouse embryo Gene Expr Patterns 2005-04-01 [PMID: 15749080] Details: This citation used the FITC version of this antibody.
Robitaille H, Proulx R, Robitaille K et al. The mitogen-activated protein kinase kinase kinase dual leucine zipper-bearing kinase (DLK) acts as a key regulator of keratinocyte terminal differentiation J Biol Chem [PMID: 15695824] Details: Used the FITC form of this antibody.
Hirai S, Kawaguchi A, Hirasawa R et al. MAPK-upstream protein kinase (MUK) regulates the radial migration of immature neurons in telencephalon of mouse embryo Development 2002-10-01 [PMID: 12223406] Details: This citation used the FITC version of this antibody.
Fukuyama K, Yoshida M, Yamashita A. MAPK upstream kinase (MUK)-binding inhibitory protein, a negative regulator of MUK/dual leucine zipper-bearing kinase/leucine zipper protein kinase J Biol Chem [PMID: 10801814] Details: Used the FITC form of this antibody.
Ito M, Yoshioka K, Akechi M. JSAP1, a novel jun N-terminal protein kinase (JNK)-binding protein that functions as a Scaffold factor in the JNK signaling pathway Mol Cell Biol [PMID: 10523642] Details: Used the FITC form of this antibody.
Douziech M, Laberge G, Grondin G et al. Localization of the mixed-lineage kinase DLK/MUK/ZPK to the Golgi apparatus in NIH 3T3 cells J Histochem Cytochem 1999-10-01 [PMID: 10490457] Details: This citation used the FITC version of this antibody.

Array NBP1-62734

• MAP3K12 Antibodies
• MAP3K12 Proteins