Lymphotoxin Antibody (135125) [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Lymphotoxin alpha , also known as tumor necrosis factor (TNF) beta , and Lymphotoxin beta are members of the TNF superfamily and have been designated TNFSF1 and TNFSF3, respectively. Secreted Lymphotoxin alpha forms a homotrimer (TNF­beta) and heterotrimeric complexes with the type II membrane protein, Lymphotoxin beta (either alpha 2 beta 1or alpha 1 beta 2 timers). These trimers serve as ligands for Lymphotoxin beta receptor, TNF RI and TNF RII and play a role in the development and maturation of the immune system.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 2 applications: Neutralization, Western Blot.

Showing Publications 1 - 3 of 3.

Publications using MAB1370	Applications	Species
H H Gari, G D DeGala, M S Lucia, J R Lambert Loss of the oncogenic phosphatase PRL-3 promotes a TNF-R1 feedback loop that mediates triple-negative breast cancer growth Oncogenesis 2016-08-15 [PMID: 27526109]
Magri G, Miyajima M, Bascones S, Mortha A, Puga I, Cassis L, Barra C, Comerma L, Chudnovskiy A, Gentile M, Llige D, Cols M, Serrano S, Arostegui J, Juan M, Yague J, Merad M, Fagarasan S, Cerutti A Innate lymphoid cells integrate stromal and immunological signals to enhance antibody production by splenic marginal zone B cells. Nat Immunol, 2014-02-23;15(4):354-64. 2014-02-23 [PMID: 24562309] (Neutralization, Human)	Neutralization	Human
Shen L, Suresh L, Wu J, Xuan J, Li H, Zhang C, Pankewycz O, Ambrus JL A role for lymphotoxin in primary Sjogren's disease. J. Immunol., 2010-10-15;185(10):6355-63. 2010-10-15 [PMID: 20952683] (Western Blot, Human, Mouse)	Western Blot	Human, Mouse

Array MAB1370

• Lymphotoxin Antibody
• Lymphotoxin Proteins and Enzymes