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Lymphotoxin-alpha/TNF-beta Antibody (pateclizumab) [CoraFluor™ 1]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, Flow, Func
Clone
pateclizumab
Clonality
Monoclonal
Host
Human
Conjugate
CoraFluor 1

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP3-28687AF350
Alexa Fluor 405
NBP3-28687AF405
Alexa Fluor 488
NBP3-28687AF488
Alexa Fluor 532
NBP3-28687AF532
Alexa Fluor 594
NBP3-28687AF594
Alexa Fluor 647
NBP3-28687AF647
Alexa Fluor 700
NBP3-28687AF700
Alexa Fluor 750
NBP3-28687AF750
Allophycocyanin
NBP3-28687APC
Biotin
NBP3-28687B
DyLight 350
NBP3-28687UV
DyLight 405
NBP3-28687V
DyLight 488
NBP3-28687G
DyLight 550
NBP3-28687R
DyLight 594
NBP3-28687DL594
DyLight 650
NBP3-28687C
DyLight 680
NBP3-28687FR
DyLight 755
NBP3-28687IR
FITC
NBP3-28687F
HRP
NBP3-28687H
Janelia Fluor 525
NBP3-28687JF525
Janelia Fluor 549
NBP3-28687JF549
Janelia Fluor 646
NBP3-28687JF646
Janelia Fluor 669
NBP3-28687JF669
PE
NBP3-28687PE
PerCP
NBP3-28687PCP
Unconjugated
NBP3-28687-100ug
mFluor Violet 450 SE
NBP3-28687MFV450
mFluor Violet 500 SE
NBP3-28687MFV500
mFluor Violet 610 SE
NBP3-28687MFV610
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Lymphotoxin-alpha/TNF-beta Antibody (pateclizumab) [CoraFluor™ 1] Summary

Description
CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
Additional Information
Recombinant Monoclonal Antibody
Immunogen
TNFSF1 / TNFb/ LT alpha
Isotype
IgG1
Clonality
Monoclonal
Host
Human
Gene
LTA
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Functional
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
No Preservative
Purity
Protein A purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for Lymphotoxin-alpha/TNF-beta Antibody (pateclizumab) [CoraFluor™ 1]

  • LT
  • LTA
  • LT-alpha
  • lymphotoxin alpha (TNF superfamily, member 1)
  • Lymphotoxin alpha
  • Lymphotoxinalpha
  • Lymphotoxin-alpha
  • tnfb
  • TNF-beta
  • TNFBlymphotoxin-alpha
  • TNFSF1
  • TNFSF1B
  • TNFSF1TNF-beta
  • tumor necrosis factor beta
  • Tumor necrosis factor ligand superfamily member 1

Background

TNF-beta (tumor necrosis factor beta, lymphotoxin alpha, TNFSF1, TNF ligand superfamily member 1) a member of the TNF ligand superfamily and a potent lymphoid factor, is mainly produced by activated T and B lymphocytes and leukocytes. TNF-beta is also produced by fibroblasts, astrocytes, myeloma cells, endothelial cells and epithelial cells. TNF-beta mediates inflammatory and immune responses, has cytotoxic activity on tumor cells and other target cells and shares many of the same bioactivities as TNF alpha, including regulation of cell proliferation, differentiation and apoptosis. TNF-beta is not species-specific and human TNF-beta is active on murine cells with a slightly reduced specific activity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Species: Hu, Mu
Applications: CyTOF-ready, Flow, ICC/IF, In vitro, WB

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol LTA