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Lymphotoxin-alpha/TNF-beta Antibody (pateclizumab) - Humanized

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, Flow, Func
Clone
pateclizumab
Clonality
Monoclonal
Host
Human
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP3-28687AF350
Alexa Fluor 405
NBP3-28687AF405
Alexa Fluor 488
NBP3-28687AF488
Alexa Fluor 532
NBP3-28687AF532
Alexa Fluor 594
NBP3-28687AF594
Alexa Fluor 647
NBP3-28687AF647
Alexa Fluor 700
NBP3-28687AF700
Alexa Fluor 750
NBP3-28687AF750
Allophycocyanin
NBP3-28687APC
Biotin
NBP3-28687B
CoraFluor 1
NBP3-28687CL1
DyLight 350
NBP3-28687UV
DyLight 405
NBP3-28687V
DyLight 488
NBP3-28687G
DyLight 550
NBP3-28687R
DyLight 594
NBP3-28687DL594
DyLight 650
NBP3-28687C
DyLight 680
NBP3-28687FR
DyLight 755
NBP3-28687IR
FITC
NBP3-28687F
HRP
NBP3-28687H
Janelia Fluor 525
NBP3-28687JF525
Janelia Fluor 549
NBP3-28687JF549
Janelia Fluor 646
NBP3-28687JF646
Janelia Fluor 669
NBP3-28687JF669
PE
NBP3-28687PE
PerCP
NBP3-28687PCP
mFluor Violet 450 SE
NBP3-28687MFV450
mFluor Violet 500 SE
NBP3-28687MFV500
mFluor Violet 610 SE
NBP3-28687MFV610
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Lymphotoxin-alpha/TNF-beta Antibody (pateclizumab) - Humanized Summary

Description
Expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.

Also known as 'pateclizumab'.

Upon receipt, store immediately at -20C or lower for 24 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles.
Additional Information
Recombinant Monoclonal Antibody
Immunogen
TNFSF1 / TNFb/ LT alpha
Isotype
IgG1
Clonality
Monoclonal
Host
Human
Gene
LTA
Purity
Protein A purified
Endotoxin Note
< 0.001EU/ug,determined by LAL method.
Innovator's Reward
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Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Functional

Packaging, Storage & Formulations

Storage
Store at 4C.
Buffer
Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)
Preservative
No Preservative
Concentration
LYOPH
Purity
Protein A purified
Reconstitution Instructions
Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.

Alternate Names for Lymphotoxin-alpha/TNF-beta Antibody (pateclizumab) - Humanized

  • LT
  • LTA
  • LT-alpha
  • lymphotoxin alpha (TNF superfamily, member 1)
  • Lymphotoxin alpha
  • Lymphotoxinalpha
  • Lymphotoxin-alpha
  • tnfb
  • TNF-beta
  • TNFBlymphotoxin-alpha
  • TNFSF1
  • TNFSF1B
  • TNFSF1TNF-beta
  • tumor necrosis factor beta
  • Tumor necrosis factor ligand superfamily member 1

Background

TNF-beta (tumor necrosis factor beta, lymphotoxin alpha, TNFSF1, TNF ligand superfamily member 1) a member of the TNF ligand superfamily and a potent lymphoid factor, is mainly produced by activated T and B lymphocytes and leukocytes. TNF-beta is also produced by fibroblasts, astrocytes, myeloma cells, endothelial cells and epithelial cells. TNF-beta mediates inflammatory and immune responses, has cytotoxic activity on tumor cells and other target cells and shares many of the same bioactivities as TNF alpha, including regulation of cell proliferation, differentiation and apoptosis. TNF-beta is not species-specific and human TNF-beta is active on murine cells with a slightly reduced specific activity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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5-Lipoxygenase
Antibody - BSA Free
NB110-58748
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Antibody - BSA Free
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(1 Review)
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Species: Hu, Mu
Applications: CyTOF-ready, Flow, ICC/IF, In vitro, WB

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Bioinformatics

Gene Symbol LTA
Uniprot