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Lunatic Fringe Antibody (SR1725)

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Western Blot: Lunatic Fringe Antibody (SR1725) [NBP3-22641] - Western blot analysis using NBP3-22641 in HeLa cell lysate.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB
Clone
SR1725
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Lunatic Fringe Antibody (SR1725) Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
A synthesized peptide derived from human Lunatic Fringe (Uniprot #: Q8NES3)
Specificity
Detects endogenous levels of total Lunatic Fringe
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
LFNG
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:2000
Theoretical MW
42 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, pH 7.4, 150mM NaCl, 50% glycerol.
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for Lunatic Fringe Antibody (SR1725)

  • beta-1,3-N-acetylglucosaminyltransferase lunatic fringe
  • EC 2.4.1.222
  • LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
  • LFNG
  • lunatic fringe (Drosophila) homolog
  • lunatic fringe homolog (Drosophila)
  • Lunatic Fringe
  • O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
  • SCDO3
  • SCDO3EC 2.4.1.222

Background

Lunatic Fringe encodes a member of the glycosyltransferase superfamily. The encoded protein is a single-pass type II Golgi membrane protein that functions as a fucose-specific glycosyltransferase, adding an N-acetylglucosamine to the fucose residue of a group of signaling receptors involved in regulating cell fate decisions during development. Mutations in this gene have been associated with autosomal recessive spondylocostal dysostosis 3. Alternatively spliced transcript variants that encode different isoforms have been described, however, not all variants have been fully characterized.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Bioinformatics

Gene Symbol LFNG