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Recombinant Human LST1 GST (N-Term) Protein

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12.5% SDS-PAGE Stained with Coomassie Blue.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, MA, AP

Order Details

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Recombinant Human LST1 GST (N-Term) Protein Summary

Description
A recombinant protein with GST tag at N-terminal corresponding to the amino acids 1-118 of Human LST1

Source: Wheat Germ (in vitro)

Amino Acid Sequence: MLSRNDDICIYGGLGLGGLLLLAVVLLSACLCWLHRRVKRLERSWPRAPQSRNSTMHLCRGCQCPAVRDLTSGAETREAPRRIQELTMPALLRTNPPEHPRHLPQPRRVDRVPLWSSQ

Preparation
Method
in vitro wheat germ expression system
Details of Functionality
This protein was produced in an in vitro wheat germ expression system that should preserve correct conformational folding that is necessary for biological function. While it is possible that this protein could display some level of activity, the functionality of this protein has not been explicitly measured or validated.
Source
Wheat germ
Protein/Peptide Type
Recombinant Protein
Gene
LST1
Purity
>80% by SDS-PAGE and Coomassie blue staining

Applications/Dilutions

Dilutions
  • ELISA
  • Immunoaffinity Purification
  • Protein Array
  • Western Blot
Theoretical MW
39.8 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
50 mM Tris-HCl, 10 mM reduced Glutathione, pH 8.0 in the elution buffer.
Preservative
No Preservative
Purity
>80% by SDS-PAGE and Coomassie blue staining

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Recombinant Human LST1 GST (N-Term) Protein

  • B144D6S49ELST-1
  • leucocyte specific transcript 1
  • leukocyte specific transcript 1
  • leukocyte-specific transcript 1 protein
  • lymphocyte antigen 117
  • MGC119006
  • MGC119007
  • Protein B144

Background

LST1, also known as Leukocyte-specific transcript 1 protein, has 10 isoforms ranging from a 13 amino acid isoform that is 1 kDa to a 97 amino acid isoform that is 11 kDa, can inhibit the proliferation of lymphocytes, induces morphological changes including production of filopodia and microspikes when overexpressed in a variety of cell types and may participate in dendritic cell maturation. Disease research is currently being performed with relation to LST1 and vulvovaginitis, rhinotracheitis, chronic venous leg ulcers, proliferative vitreoretinopathy, systemic lupus erythematosus, vitreoretinopathy, rubella, lupus erythematosus, tonsillitis, diabetes mellitus, lung cancer, and Graves' disease. Interactions with this protein have been shown to involve G2E3, PRKCB and CACTIN in cell morphogenesis, immune response, regulation of cell shape, anatomical structure morphogenesis, and dendrite development pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Array H00007940-P01

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Bioinformatics

Gene Symbol LST1