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LRP-6 Antibody (255302) [Phycoerythrin]

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MDA-MB-231 human breast cancer cell line was stained with Mouse Anti-Human LRP-6 PE-conjugated Monoclonal Antibody (Catalog # FAB1505P, filled histogram) or isotype control antibody (Catalog # IC003P, open histogram). View our protocol for Staining Membrane-associated Proteins.
MDA-MB-231 human breast cancer cell line was stained with Mouse Anti-Human LRP-6 PE-conjugated Monoclonal Antibody (Catalog # FAB1505P, filled histogram) or isotype control antibody (Catalog # IC003P, open histogram). ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
255302
Clonality
Monoclonal
Host
Mouse
Conjugate
Phycoerythrin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB1505U-100UG
Alexa Fluor 405
FAB1505V-100UG
Alexa Fluor 488
FAB1505G-100UG
Alexa Fluor 532
FAB1505X
Alexa Fluor 594
FAB1505T-100UG
Alexa Fluor 647
FAB1505R-100UG
Alexa Fluor 700
FAB1505N-100UG
Alexa Fluor 750
FAB1505S-100UG
Allophycocyanin
FAB1505A
Allophycocyanin/Cy7
FAB1505APCCY7
Biotin
FAB1505B
CoraFluor 1
FAB1505CL1
DyLight 350
FAB1505D
DyLight 405
FAB1505E
DyLight 488
FAB1505K
DyLight 550
FAB1505L
DyLight 594
FAB1505M
DyLight 650
FAB1505W
DyLight 680
FAB1505Y
DyLight 755
FAB1505Z
FITC
FAB1505F
HRP
FAB1505H
Janelia Fluor 525
FAB1505JF525
Janelia Fluor 549
FAB1505I
Janelia Fluor 646
FAB1505J
Janelia Fluor 669
FAB1505JF669
PE/Atto594
FAB1505PEATT594
PE/Cy5.5
FAB1505PECY55
PE/Cy7
FAB1505PECY7
PerCP
FAB1505C
Unconjugated
MAB1505
mFluor Violet 450 SE
FAB1505MFV450
mFluor Violet 500 SE
FAB1505MFV500
mFluor Violet 610 SE
FAB1505MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB1505
Carrier Free
MAB1505
Carrier Free
FAB1505A
Carrier Free
MAB1505-SP
Carrier Free
FAB1505V-100UG
Carrier Free
FAB1505U-100UG
Carrier Free
FAB1505T-100UG
Carrier Free
FAB1505S-100UG
Carrier Free
FAB1505R-100UG
Carrier Free
FAB1505N-100UG
Carrier Free
FAB1505G-100UG
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LRP-6 Antibody (255302) [Phycoerythrin] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human LRP-6
Ala20-Pro1368
Accession # O75581
Specificity
Detects human LRP-6 in direct ELISAs. In direct ELISAs, approximately 5% cross-reactivity with recombinant mouse (rm) LRP-6 and no cross-reactivity with recombinant human (rh) LRP-1, -4, -5, rhLRP-6 (intracellular domain), or rhLDL R is observed.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
LRP6
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for LRP-6 Antibody (255302) [Phycoerythrin]

  • ADCAD2
  • FLJ90062
  • FLJ90421
  • low density lipoprotein receptor-related protein 6
  • low-density lipoprotein receptor-related protein 6
  • LRP6
  • LRP-6

Background

LRP-6 (Low-density lipoprotein receptor-related protein 6) is a 200-210 kDa member of the LDLR family of proteins. It is widely expressed, and serves as a coreceptor for both Wnt and parathyroid hormone. In the Wnt system, LRP-6 associates with select Fzd multipass receptors; in the PTH system, LRP-6 complexes with PTH1R. Mature human LRP-6 is a 1594 amino acid (aa) type I transmembrane glycoprotein. It contains a 1351 aa extracellular region (aa 20-1370) plus a 220 aa cytoplasmic domain (aa 1394-1613). The cytoplasmic domain contains two palmitoylation sites, one ubiquitination residue, and multiple phosphorylation motifs.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol LRP6
Uniprot