LRP-6 Antibody (255302) [Allophycocyanin]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

LRP-6 (Low-density lipoprotein receptor-related protein 6) is a 200-210 kDa member of the LDLR family of proteins. It is widely expressed, and serves as a coreceptor for both Wnt and parathyroid hormone. In the Wnt system, LRP-6 associates with select Fzd multipass receptors; in the PTH system, LRP-6 complexes with PTH1R. Mature human LRP-6 is a 1594 amino acid (aa) type I transmembrane glycoprotein. It contains a 1351 aa extracellular region (aa 20-1370) plus a 220 aa cytoplasmic domain (aa 1394-1613). The cytoplasmic domain contains two palmitoylation sites, one ubiquitination residue, and multiple phosphorylation motifs.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: Flow Cytometry.

Showing Publications 1 - 2 of 2.

Publications using FAB1505A	Applications	Species
Y Ghaleb, S Elbitar, A Philippi, P El Khoury, Y Azar, M Andrianiri, A Loste, Y Abou-Khali, G Nicolas, M Le Borgne, P Moulin, M Di-Filippo, S Charrière, M Farnier, C Yelnick, V Carreau, J Ferrières, JM Lecerf, A Derksen, G Bernard, MS Gauthier, B Coulombe, D Lütjohann, B Fin, A Boland, R Olaso, JF Deleuze, JP Rabès, C Boileau, M Abifadel, M Varret Whole Exome/Genome Sequencing Joint Analysis of a Family with Oligogenic Familial Hypercholesterolemia Metabolites, 2022-03-18;12(3):. 2022-03-18 [PMID: 35323704] (Flow Cytometry, Human)	Flow Cytometry	Human
BS Berger, SP Acebron, J Herbst, S Koch, C Niehrs Parkinson's disease-associated receptor GPR37 is an ER chaperone for LRP6 EMBO Rep, 2017-03-24;0(0):. 3/24/2017 [PMID: 28341812]

Array FAB1505A

• LRP-6 Antibodies
• LRP-6 ELISA Kit
• LRP-6 Lysate
• LRP-6 Proteins and Enzymes