| Reactivity | HuSpecies Glossary |
| Applications | Flow, Flow |
| Clone | 508921 |
| Clonality | Monoclonal |
| Host | Mouse |
| Conjugate | Phycoerythrin |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human LAMP1/CD107a Ala28-Asn380 Accession # P11279 |
| Specificity | Detects human LAMP1/CD107a in direct ELISAs and Western blots. |
| Source | N/A |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Host | Mouse |
| Gene | LAMP1 |
| Purity Statement | Protein A or G purified from hybridoma culture supernatant |
| Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
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| Storage | Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light. |
| Buffer | Supplied in a saline solution containing BSA and Sodium Azide. |
| Preservative | Sodium Azide |
Lysosome-associated membrane protein-1 (LAMP1), also known as CD107a, is a 100‑130 kDa member of the LAMP family of glycoproteins. It is expressed in lysosomal and plasma membranes of macrophages, NK and T-cells, and with LAMP2, is essential for the formation of phagolysosomes. On the cell surface, it also presents carbohydrates to selectins. Mature human LAMP1 is a 389 amino acid (aa) type I transmembrane glycoprotein. It contains a 354 aa luminal/extracellular domain (ECD) (aa 28‑381) and a 12 aa cytoplasmic tail (aa 405‑416). The ECD has two large looping regions (aa 28‑193 and 227‑381) plus multiple N- and O-linked glycosylation sites. There is one potential splice variant that shows a 26 aa substitution in the signal sequence. Over aa 28‑380, human LAMP1 shares 64% aa identity with mouse LAMP1.
![LAMP-1/CD107a Antibody (508921) [Phycoerythrin]](/sites/all/modules/enterprise-tech/et_datasheets/images/novus_guarantee.png "LAMP-1/CD107a Antibody (508921) [Phycoerythrin]")
Secondary Antibodies |
Isotype Controls |
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