LAIR1 Antibody (342219) [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Leukocyte-associated Ig-like receptor-1 (LAIR1; also CD305) is a 46 kDa inhibitory receptor belonging to the Ig superfamily. It is a type I transmembrane protein with one extracellular Ig-like domain and two cytoplasmic ITIMs. Four LAIR-1 splice variants exist. LAIR1b has a 17 aa deletion outside the Ig loop in the extracellular domain. It differs from LAIR1c by one aa residue. LAIR1d has a 77 aa truncation in the cytoplasmic domain. LAIR1 is expressed on NK cells, T cells, B cells, monocytes, dendritic cells and most thymocytes. The extracellular domain of human LAIR1 shares 40% aa identity with that of the mouse protein.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: Flow Cytometry, Western Blot.

Showing Publications 1 - 2 of 2.

Publications using MAB2664	Applications	Species
AO Achieng, B Guyah, Q Cheng, JM Ong'echa, C Ouma, CG Lambert, DJ Perkins Molecular basis of reduced LAIR1 expression in childhood severe malarial anaemia: Implications for leukocyte inhibitory signalling EBioMedicine, 2019-06-27;45(0):278-289. 2019-06-27 [PMID: 31257148] (Western Blot, Human)	Western Blot	Human
Cabezon R, Sintes J, Llinas L, Benitez-Ribas D Analysis of HLDA9 mAbs on plasmacytoid dendritic cells. Immunol. Lett., 2010-10-07;134(2):167-73. 2010-10-07 [PMID: 20933012] (Flow Cytometry, Human)	Flow Cytometry	Human

Array MAB2664

• LAIR1 Antibodies
• LAIR1 Lysate
• LAIR1 Protein
• LAIR1 ELISA
• LAIR1 Proteins and Enzymes