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LAIR1 Antibody (342219) [Allophycocyanin]

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Human peripheral blood lymphocytes were stained with Mouse Anti-Human LAIR1 APC-conjugated Monoclonal Antibody (Catalog # FAB2664A, filled histogram) or isotype control antibody (Catalog # IC0041A, open histogram). View ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
342219
Clonality
Monoclonal
Host
Mouse
Conjugate
Allophycocyanin

Order Details

LAIR1 Antibody (342219) [Allophycocyanin] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human LAIR1 isoform 1
Gln22-His163
Accession # Q6GTX8
Specificity
Detects human LAIR1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human LAIR2 or recombinant mouse LAIR1 is observed.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
LAIR1
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for LAIR1 Antibody (342219) [Allophycocyanin]

  • CD305 antigen
  • CD305
  • CD305leukocyte-associated Ig-like receptor 1
  • HLAIR1
  • LAIR1
  • LAIR-1
  • leukocyte-associated immunoglobulin-like receptor 1

Background

Leukocyte-associated Ig-like receptor-1 (LAIR1; also CD305) is a 46 kDa inhibitory receptor belonging to the Ig superfamily. It is a type I transmembrane protein with one extracellular Ig-like domain and two cytoplasmic ITIMs. Four LAIR-1 splice variants exist. LAIR1b has a 17 aa deletion outside the Ig loop in the extracellular domain. It differs from LAIR1c by one aa residue. LAIR1d has a 77 aa truncation in the cytoplasmic domain. LAIR1 is expressed on NK cells, T cells, B cells, monocytes, dendritic cells and most thymocytes. The extracellular domain of human LAIR1 shares 40% aa identity with that of the mouse protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol LAIR1
Uniprot