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Laforin/EPM2A Antibody - BSA Free

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Western Blot: Laforin/EPM2A Antibody [NBP2-81945] - Analysis of Laforin/EPM2A in SW480 cell lysate with Laforin/EPM2A antibody at (A) 1 and (B) 2 ug/ml.
Immunocytochemistry/ Immunofluorescence: Laforin/EPM2A Antibody [NBP2-81945] - Analysis of Laforin/EPM2A in SW480 cells with Laforin/EPM2A antibody at 5 ug/ml.
Immunocytochemistry/ Immunofluorescence: Laforin/EPM2A Antibody [NBP2-81945] - Analysis of Laforin/EPM2A in SW480 cells with Laforin/EPM2A antibody at 2.5 ug/ml.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
1 mg/ml

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Laforin/EPM2A Antibody - BSA Free Summary

Immunogen
EPM2A antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human EPM2A. The immunogen is located within amino acids 190 - 240 of EPM2A. Amino Acid Squence: NRYPEPMTPDTMIKLY
Specificity
At least four isoforms of Laforin/EPM2A are known to exist; this antibody will detect all but the shortest isoform.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
EPM2A
Purity
Peptide affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot 1-2 ug/ml
Theoretical MW
36 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Peptide affinity purified

Alternate Names for Laforin/EPM2A Antibody - BSA Free

  • EC 3.1.3.16
  • EC 3.1.3.48
  • epilepsy, progressive myoclonus type 2, Lafora disease (laforin)
  • epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
  • EPM2
  • EPM2A
  • Lafora PTPase
  • Laforin
  • LAFPTPase
  • LD
  • LDE
  • MELF

Background

EPM2A encodes a dual-specificity phosphatase that associates with polyribosomes. The encoded protein may be involved in the regulation of glycogen metabolism. Mutations in this gene have been associated with myoclonic epilepsy of Lafora. Alternative splicing results in multiple transcript variants. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol EPM2A