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Laforin/EPM2A Antibody [Janelia Fluor® 525]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Janelia Fluor 525

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-81945AF350
Alexa Fluor 405
NBP2-81945AF405
Alexa Fluor 488
NBP2-81945AF488
Alexa Fluor 532
NBP2-81945AF532
Alexa Fluor 594
NBP2-81945AF594
Alexa Fluor 647
NBP2-81945AF647
Alexa Fluor 700
NBP2-81945AF700
Alexa Fluor 750
NBP2-81945AF750
Biotin
NBP2-81945B
CoraFluor 1
NBP2-81945CL1
DyLight 350
NBP2-81945UV
DyLight 405
NBP2-81945V
DyLight 488
NBP2-81945G
DyLight 550
NBP2-81945R
DyLight 594
NBP2-81945DL594
DyLight 650
NBP2-81945C
DyLight 680
NBP2-81945FR
DyLight 755
NBP2-81945IR
FITC
NBP2-81945F
HRP
NBP2-81945H
Janelia Fluor 549
NBP2-81945JF549
Janelia Fluor 585
NBP2-81945JF585
Janelia Fluor 635
NBP2-81945JF635
Janelia Fluor 646
NBP2-81945JF646
Janelia Fluor 669
NBP2-81945JF669
PerCP
NBP2-81945PCP
Unconjugated
NBP2-81945
mFluor Violet 450 SE
NBP2-81945MFV450
mFluor Violet 500 SE
NBP2-81945MFV500
mFluor Violet 610 SE
NBP2-81945MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-81945
BSA Free
NBP2-81945
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Laforin/EPM2A Antibody [Janelia Fluor® 525] Summary

Immunogen
EPM2A antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human EPM2A. The immunogen is located within amino acids 190 - 240 of EPM2A. Amino Acid Squence: NRYPEPMTPDTMIKLY
Specificity
At least four isoforms of Laforin/EPM2A are known to exist; this antibody will detect all but the shortest isoform.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
EPM2A
Purity
Peptide affinity purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Peptide affinity purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Laforin/EPM2A Antibody [Janelia Fluor® 525]

  • EC 3.1.3.16
  • EC 3.1.3.48
  • epilepsy, progressive myoclonus type 2, Lafora disease (laforin)
  • epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
  • EPM2
  • EPM2A
  • Lafora PTPase
  • Laforin
  • LAFPTPase
  • LD
  • LDE
  • MELF

Background

EPM2A encodes a dual-specificity phosphatase that associates with polyribosomes. The encoded protein may be involved in the regulation of glycogen metabolism. Mutations in this gene have been associated with myoclonic epilepsy of Lafora. Alternative splicing results in multiple transcript variants. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol EPM2A