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Kallikrein 3/PSA Antibody (RM323)

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Western Blot: Kallikrein 3/PSA Antibody (RM323) [NBP2-77416] - Western Blot of PSA (purified from human seminal fluid), ACT (alpha 1-antichymotrypsin, from human plasma), and PSA-ACT complex, under non-reduced (-) or ...read more
Immunohistochemistry: Kallikrein 3/PSA Antibody (RM323) [NBP2-77416] - Immunohistochemical staining of formalin fixed and paraffin embedded human prostate cancer tissue section using NBP2-77416.
ELISA: Kallikrein 3/PSA Antibody (RM323) [NBP2-77416] - A titer ELISA of PSA (purified from human seminal fluid). The plate was coated with different amounts of PSA. A serial dilution of NBP2-77416 was used as the ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, IHC
Clone
RM323
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Kallikrein 3/PSA Antibody (RM323) Summary

Additional Information
Recombinant Monoclonal Antibody.
Immunogen
Native Kallikrein 3/PSA protein purified from human seminal fluid
Specificity
This antibody reacts to native human Kallikrein 3/PSA, including both free (unbound) form and in a complex with ACT (alpha 1-antichymotrypsin). It may react to reduced Kallikrein 3/PSA at a higher concentration.
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
KLK3
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • ELISA 1:100 - 1:5000
  • Immunohistochemistry 1:500 - 1:1000
  • Western Blot 1:1000 - 1:2500 (non-reducing conditions)

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
50% Glycerol/PBS, 1% BSA
Preservative
0.09% Sodium Azide
Purity
Protein A purified

Alternate Names for Kallikrein 3/PSA Antibody (RM323)

  • APS seminin
  • EC 3.4.21
  • EC 3.4.21.77
  • Gamma-seminoprotein
  • hK3
  • Kallikrein 3
  • kallikrein 3, (prostate specific antigen)
  • Kallikrein-3
  • kallikrein-related peptidase 3
  • KLK2A1
  • KLK3
  • P-30 antigen
  • prostate specific antigen
  • prostate-specific antigen
  • PSA semenogelase
  • PSA
  • Semenogelase
  • Seminin

Background

PSA is a chymotrypsin-like serine protease (kallikrein family) produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liverderived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol KLK3