![Immunohistochemistry-Paraffin: Kallikrein 3/PSA Antibody (1A7 (same as 1A7G6B6)) - IHC-Prediluted [NBP2-48324] - Formalin-fixed, paraffin-embedded human Prostate Carcinoma.](http://images.novusbio.com/fullsize/Kallikrein-3-PSA-Antibody-1A7-same-as-1A7G6B6-IHC-Prediluted-Immunohistochemistry-Paraffin-NBP2-48324-img0001.jpg "Immunohistochemistry-Paraffin: Kallikrein 3/PSA Antibody (1A7 (same as 1A7G6B6)) - IHC-Prediluted [NBP2-48324] - Formalin-fixed, paraffin-embedded human Prostate Carcinoma.")
| Reactivity | Hu, FeSpecies Glossary |
| Applications | IHC |
| Clone | 1A7 |
| Clonality | Monoclonal |
| Host | Mouse |
| Conjugate | Unconjugated |
| Format | IHC-Prediluted |
| Description | The prediluted antibody does not require any mixing, dilution, reconstitution, or titration; the antibody is ready-to-use and optimized for staining. |
| Immunogen | Kallikrein 3/PSA from human sperm plasma (Uniprot: P07288) |
| Localization | Cytoplasmic |
| Specificity | Recognizes a single protein of 33-34kDa, identified as the prostate specific antigen (PSA). This monoclonal antibody is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues. PSA is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia. This monoclonal antibody makes an excellent pair with monoclonal antibody A67-B/E3 for PSA tests. |
| Isotype | IgG1 Kappa |
| Clonality | Monoclonal |
| Host | Mouse |
| Gene | KLK3 |
| Purity | Protein A or G purified |
| Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
| Dilutions |
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| Application Notes | Immunohistochemistry (Formalin-fixed): 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes. Optimal dilution for a specific application should be determined. |
| Storage | Store at 4C. |
| Buffer | 10 mM PBS with 0.05% BSA |
| Preservative | 0.05% Sodium Azide |
| Purity | Protein A or G purified |
Secondary Antibodies |
Isotype Controls |
Research Areas for Kallikrein 3/PSA Antibody (NBP2-48324)Find related products by research area.
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| Gene Symbol | KLK3 |
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