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Kallikrein 1 Antibody

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Western Blot: Kallikrein 1 Antibody [NB100-57855] - Analysis of Kallikrein 1 in human kidney lysate (35ug protein in RIPA buffer) using NB100-57855 at 0.1ug/ml.
Western Blot: Kallikrein 1 Antibody [NB100-57855] - (0.5ug/ml) staining of Human Kidney lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

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Kallikrein 1 Antibody Summary

Immunogen
Peptide with sequence PNDECKKAHVQK corresponding to internal region according to NP_002248.1.
Epitope
PNDECKKAHVQK
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
KLK1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Peptide ELISA Detection limit 1:2000
  • Western Blot 1 - 3 ug/ml
Application Notes
WB: Approx. 55 kDa band observed in human kidney, pancreas and skin lysates is reported in scientific literature (PMID: 17259996).
Control
Human Kidney Whole Tissue Lysate (Adult Whole Normal)
Kallikrein 1 Overexpression Lysate
Publications
Read Publications using NB100-57855.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Kallikrein 1 Antibody

  • EC 3.4.21
  • EC 3.4.21.35
  • glandular kallikrein 1
  • hK1
  • Kallikrein 1
  • kallikrein 1, renal/pancreas/salivary
  • kallikrein serine protease 1
  • kallikrein-1
  • Kidney/pancreas/salivary gland kallikrein
  • KLK1
  • Klk6
  • KLKR
  • Tissue kallikrein

Background

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. This protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Kallikrein 1 Antibody (NB100-57855)(2)

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Product General Protocols

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Video Protocols

WB Video Protocol

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Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol KLK1
Entrez
Uniprot