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Jagged 2 Antibody

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Western Blot: Jagged 2 Antibody [NBP2-27420] - Analysis of JAG2 in mouse thymus lysate using 1) prebleed at 1:5000 dilution and 2) this antibody. Goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.
Western Blot: Jagged 2 Antibody [NBP2-27420] - Analysis of JAG2 in mouse thymus lysate using 1) prebleed at 1:5000 dilution and 2) this antibody. Goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate ...read more

Product Details

Summary
Reactivity Hu, Pm, Mu, Rt, Eq, PmSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

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Jagged 2 Antibody Summary

Immunogen
A portion of amino acids 150-210 of human JAG2 was used as the immunogen.
Predicted Species
Mouse (94%), Rat (94%), Monkey (100%), Equine (94%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
JAG2
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Western Blot 5-10ug/ml

Reactivity Notes

The amino acid sequence used as immunogen is 100% homologous in monkey, 94% homologous in mouse, rat and horse, 76% homologous in opossum and 70% homologous in chicken.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
0.2 ml PBS and 0.05% BSA
Preservative
0.05% Sodium Azide
Concentration
0.5 mg/ml
Purity
Protein A purified

Alternate Names for Jagged 2 Antibody

  • HJ2
  • JAG2
  • Jagged 2
  • Jagged2
  • protein jagged-2
  • SER2

Background

Protein jagged-2 (JAG2)is a Notch signaling pathway protein which is a ligand for Notch-1. It is a single-pass type 1 membrane protein which contains one DSL domain, sixteen EGF-like domains and one VWFC domain. JAG2, along with JAG1, DLL3 and DLL1 act as predominant Notch ligands, which have overlapping receptor binding specificities. JAG2 is also reported to regulating the expression of cytokines that can promote antitumor immunity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol JAG2
Uniprot